The promise of adolescence: Realizing opportunity for all youth

EP Backes, RJ Bonnie - 2019 - books.google.com
Adolescenceâ€" beginning with the onset of puberty and ending in the mid-20sâ€" is a
critical period of development during which key areas of the brain mature and develop …

Neurobiological and systemic effects of chronic stress

BS McEwen - Chronic stress, 2017 - journals.sagepub.com
The brain is the central organ of stress and adaptation to stress because it perceives and
determines what is threatening, as well as the behavioral and physiological responses to the …

[图书][B] The evolution of the sensitive soul: Learning and the origins of consciousness

S Ginsburg, E Jablonka - 2019 - books.google.com
A new theory about the origins of consciousness that finds learning to be the driving force in
the evolutionary transition to basic consciousness. What marked the evolutionary transition …

Stress effects on neuronal structure: hippocampus, amygdala, and prefrontal cortex

BS McEwen, C Nasca, JD Gray - Neuropsychopharmacology, 2016 - nature.com
The hippocampus provided the gateway into much of what we have learned about stress
and brain structural and functional plasticity, and this initial focus has expanded to other …

Treatment resistant depression: a multi-scale, systems biology approach

H Akil, J Gordon, R Hen, J Javitch, H Mayberg… - Neuroscience & …, 2018 - Elsevier
An estimated 50% of depressed patients are inadequately treated by available interventions.
Even with an eventual recovery, many patients require a trial and error approach, as there …

[HTML][HTML] Brain changes in a maternal immune activation model of neurodevelopmental brain disorders

L Bergdolt, A Dunaevsky - Progress in neurobiology, 2019 - Elsevier
The developing brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …

In pursuit of resilience: stress, epigenetics, and brain plasticity

BS McEwen - Annals of the New York Academy of Sciences, 2016 - Wiley Online Library
The brain is the central organ for adaptation to experiences, including stressors, which are
capable of changing brain architecture as well as altering systemic function through …

[HTML][HTML] Recognizing resilience: Learning from the effects of stress on the brain

BS McEwen, JD Gray, C Nasca - Neurobiology of stress, 2015 - Elsevier
As the central organ of stress and adaptation to stressors, the brain plays a pivotal role in
behavioral and physiological responses that may lead to successful adaptation or to …

Regulation of alternative splicing through coupling with transcription and chromatin structure

S Naftelberg, IE Schor, G Ast… - Annual review of …, 2015 - annualreviews.org
Alternative precursor messenger RNA (pre-mRNA) splicing plays a pivotal role in the flow of
genetic information from DNA to proteins by expanding the coding capacity of genomes …

Genomic and epigenomic mechanisms of glucocorticoids in the brain

JD Gray, JF Kogan, J Marrocco… - Nature Reviews …, 2017 - nature.com
Following the discovery of glucocorticoid receptors in the hippocampus and other brain
regions, research has focused on understanding the effects of glucocorticoids in the brain …