Harnessing the biology of IL-7 for therapeutic application
CL Mackall, TJ Fry, RE Gress - Nature Reviews Immunology, 2011 - nature.com
Abstract Interleukin-7 (IL-7) is required for T cell development and for maintaining and
restoring homeostasis of mature T cells. IL-7 is a limiting resource under normal conditions …
restoring homeostasis of mature T cells. IL-7 is a limiting resource under normal conditions …
Immune reconstitution under antiretroviral therapy: the new challenge in HIV-1 infection
P Corbeau, J Reynes - Blood, The Journal of the American …, 2011 - ashpublications.org
Although highly active antiretroviral therapy has enabled constant progress in reducing HIV-
1 replication, in some patients who are “aviremic” during treatment, the problem of …
1 replication, in some patients who are “aviremic” during treatment, the problem of …
Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells
MM Lederman, L Calabrese… - Journal of Infectious …, 2011 - academic.oup.com
Background. Failure to normalize CD4+ T-cell numbers despite effective antiretroviral
therapy is an important problem in human immunodeficiency virus (HIV) infection. Methods …
therapy is an important problem in human immunodeficiency virus (HIV) infection. Methods …
Incomplete immune recovery in HIV infection: mechanisms, relevance for clinical care, and possible solutions
JC Gaardbo, HJ Hartling, J Gerstoft… - Journal of Immunology …, 2012 - Wiley Online Library
Treatment of HIV‐infected patients with highly active antiretroviral therapy (HAART) usually
results in diminished viral replication, increasing CD4+ cell counts, a reversal of most …
results in diminished viral replication, increasing CD4+ cell counts, a reversal of most …
The Absence of CD4+ T Cell Count Recovery Despite Receipt of Virologically Suppressive Highly Active Antiretroviral Therapy: Clinical Risk, Immunological Gaps …
L Gazzola, C Tincati, GM Bellistré… - Clinical Infectious …, 2009 - academic.oup.com
Up to 30% of human immunodeficiency virus (HIV)–infected patients who are receiving long-
term highly active antiretroviral therapy do not exhibit a marked increase in the CD4+ T cell …
term highly active antiretroviral therapy do not exhibit a marked increase in the CD4+ T cell …
[HTML][HTML] The effects of twenty-four nutrients and phytonutrients on immune system function and inflammation: A narrative review
J Poles, E Karhu, M McGill, HR McDaniel… - Journal of clinical and …, 2021 - ncbi.nlm.nih.gov
Methods: A comprehensive literature search of PubMed was performed to find clinical trials
in humans that assessed the effect of nutrients and phytonutrients on immune function and …
in humans that assessed the effect of nutrients and phytonutrients on immune function and …
Randomized, controlled clinical trial of zinc supplementation to prevent immunological failure in HIV-infected adults
MK Baum, S Lai, S Sales, JB Page… - Clinical infectious …, 2010 - academic.oup.com
Background. Adequate zinc is critical for immune function; however, zinc deficiency occurs
in 150% of human immunodeficiency virus (HIV)-infected adults. We examined the safety …
in 150% of human immunodeficiency virus (HIV)-infected adults. We examined the safety …
Risk, predictors, and mortality associated with non-AIDS events in newly diagnosed HIV-infected patients: role of antiretroviral therapy
Objective: We aimed to characterize non-AIDS events (NAEs) occurring in newly diagnosed
HIV-infected patients in a contemporary cohort. Methods: The Cohort of the AIDS Research …
HIV-infected patients in a contemporary cohort. Methods: The Cohort of the AIDS Research …
Definition of advanced age in HIV infection: looking for an age cut-off
The age of 50 has been considered as a cut-off to discriminate older subjects within HIV-
infected people according to the Centers for Disease Control and Prevention (CDC) …
infected people according to the Centers for Disease Control and Prevention (CDC) …
Discordant immune response with antiretroviral therapy in HIV-1: a systematic review of clinical outcomes
Background A discordant immune response (DIR) is a failure to satisfactorily increase CD4
counts on ART despite successful virological control. Literature on the clinical effects of DIR …
counts on ART despite successful virological control. Literature on the clinical effects of DIR …