Clonal hematopoiesis and measurable residual disease assessment in acute myeloid leukemia
RP Hasserjian, DP Steensma… - Blood, The Journal …, 2020 - ashpublications.org
Current objectives regarding treatment of acute myeloid leukemia (AML) include achieving
complete remission (CR) by clinicopathological criteria followed by interrogation for the …
complete remission (CR) by clinicopathological criteria followed by interrogation for the …
The genesis and evolution of acute myeloid leukemia stem cells in the microenvironment: From biology to therapeutic targeting
Y Chen, J Li, L Xu, MA Găman, Z Zou - Cell Death Discovery, 2022 - nature.com
Acute myeloid leukemia (AML) is a hematological malignancy characterized by cytogenetic
and genomic alterations. Up to now, combination chemotherapy remains the standard …
and genomic alterations. Up to now, combination chemotherapy remains the standard …
A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia
The treatment landscape of acute myeloid leukemia (AML) is evolving, with promising
therapies entering clinical translation, yet patient responses remain heterogeneous, and …
therapies entering clinical translation, yet patient responses remain heterogeneous, and …
[HTML][HTML] Oral azacitidine maintenance therapy for acute myeloid leukemia in first remission
Background Although induction chemotherapy results in remission in many older patients
with acute myeloid leukemia (AML), relapse is common and overall survival is poor …
with acute myeloid leukemia (AML), relapse is common and overall survival is poor …
MRD tailored therapy in AML: what we have learned so far
LL Ngai, A Kelder, JJWM Janssen… - Frontiers in …, 2021 - frontiersin.org
Acute myeloid leukemia (AML) is a heterogeneous clonal disease associated with a dismal
survival, partly due to the frequent occurrence of relapse. Many patient-and leukemia …
survival, partly due to the frequent occurrence of relapse. Many patient-and leukemia …
Long noncoding RNAs: a novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia
A Kirtonia, M Ashrafizadeh, A Zarrabi… - Journal of cellular …, 2022 - Wiley Online Library
Acute myeloid leukemia (AML) is a common hematological disorder with heterogeneous
nature that resulted from blocked myeloid differentiation and an enhanced number of …
nature that resulted from blocked myeloid differentiation and an enhanced number of …
Reproducible measurable residual disease detection by multiparametric flow cytometry in acute myeloid leukemia
MA Röhnert, M Kramer, J Schadt, P Ensel, C Thiede… - Leukemia, 2022 - nature.com
Measurable residual disease (MRD) detected by multiparametric flow cytometry (MFC) is
associated with unfavorable outcome in patients with AML. A simple, broadly applicable …
associated with unfavorable outcome in patients with AML. A simple, broadly applicable …
Measurable residual disease (MRD) as a surrogate efficacy-response biomarker in AML
E Meddi, A Savi, F Moretti, F Mallegni… - International Journal of …, 2023 - mdpi.com
In acute myeloid leukemia (AML) many patients experience relapse, despite the
achievement of morphological complete remission; therefore, conventional morphologic …
achievement of morphological complete remission; therefore, conventional morphologic …
Integrating holotomography and deep learning for rapid detection of NPM1 mutations in AML
Rapid and accurate diagnosis of acute myeloid leukemia (AML) remains a significant
challenge, particularly in the context of myelodysplastic syndrome (MDS) or MDS …
challenge, particularly in the context of myelodysplastic syndrome (MDS) or MDS …
Proteome and phosphoproteome changes associated with prognosis in acute myeloid leukemia
E Aasebø, FS Berven, S Bartaula-Brevik, T Stokowy… - Cancers, 2020 - mdpi.com
Acute myeloid leukemia (AML) is a hematological cancer that mainly affects the elderly.
Although complete remission (CR) is achieved for the majority of the patients after induction …
Although complete remission (CR) is achieved for the majority of the patients after induction …