The functionalization of C–H bonds has created new approaches to preparing organic
molecules by enabling new strategic “disconnections” during the planning of a synthetic …

The direct functionalization of C H bonds in organic compounds has recently emerged as a
powerful and ideal method for the formation of carbon–carbon and carbon–heteroatom …

Discovery chemists routinely identify purpose-tailored molecules through an iterative
structural optimization approach, but the preparation of each successive candidate in a …

Transition-metal-catalyzed C–H bond functionalizations have had an enormous influence on
organic synthesis in recent times. However, the use of low-abundance 4d and 5d metals is …

The site-selective formation of carbonrcarbon bonds through direct functionalizations of
otherwise unreactive carbonrhydrogen bonds constitutes an economically attractive strategy …

Functionalizing traditionally inert carbon–hydrogen bonds represents a powerful
transformation in organic synthesis, providing new entries to valuable structural motifs and …

Pyridines are among the most prevalent heterocyclic structural units in pharmaceutical and
agrochemical targets, as well as in materials science (Figure 1). 1 Pyridines also provide …

The area of transition‐metal‐catalyzed direct arylation through cleavage of C H bonds has
undergone rapid development in recent years, and is becoming an increasingly viable …

In recent years, transition metal‐catalyzed direct (hetero) arylation reactions of heteroarenes
with (hetero) aryl halides and pseudohalides have received significant attention as eco …

Die direkte Funktionalisierung von C‐H‐Bindungen in organischen Molekülen hat sich in
jüngster Zeit zu einer wirksamen und idealen Methode entwickelt, mit der Kohlenstoff …