Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics

S Simpson, MD Dunning, S de Brot… - Acta Veterinaria …, 2017 - Springer
Osteosarcoma (OSA) is a rare cancer in people. However OSA incidence rates in dogs are
27 times higher than in people. Prognosis in both species is relatively poor, with 5 year OSA …

Demographic history, selection and functional diversity of the canine genome

EA Ostrander, RK Wayne, AH Freedman… - Nature Reviews …, 2017 - nature.com
The domestic dog represents one of the most dramatic long-term evolutionary experiments
undertaken by humans. From a large wolf-like progenitor, unparalleled diversity in …

Longevity and mortality of owned dogs in England

DG O'neill, DB Church, PD McGreevy, PC Thomson… - The Veterinary …, 2013 - Elsevier
Improved understanding of longevity represents a significant welfare opportunity for the
domestic dog, given its unparalleled morphological diversity. Epidemiological research …

Mortality in North American dogs from 1984 to 2004: an investigation into age‐, size‐, and breed‐related causes of death

JM Fleming, KE Creevy… - Journal of Veterinary …, 2011 - Wiley Online Library
Background: Anecdotal beliefs and limited research suggest variable patterns of mortality in
age, size, and breed cohorts of dogs. Detailed knowledge of mortality patterns would …

Prevalence of disorders recorded in dogs attending primary-care veterinary practices in England

DG O′ Neill, DB Church, PD McGreevy, PC Thomson… - PloS one, 2014 - journals.plos.org
Purebred dog health is thought to be compromised by an increasing occurence of inherited
diseases but inadequate prevalence data on common disorders have hampered efforts to …

The size–life span trade-off decomposed: why large dogs die young

C Kraus, S Pavard… - The American …, 2013 - journals.uchicago.edu
Large body size is one of the best predictors of long life span across species of mammals. In
marked contrast, there is considerable evidence that, within species, larger individuals are …

The effect of inbreeding, body size and morphology on health in dog breeds

D Bannasch, T Famula, J Donner, H Anderson… - Canine Medicine and …, 2021 - Springer
Background Dog breeds are known for their distinctive body shape, size, coat color, head
type and behaviors, features that are relatively similar across members of a breed …

The dog aging project: translational geroscience in companion animals

M Kaeberlein, KE Creevy, DEL Promislow - Mammalian genome, 2016 - Springer
Studies of the basic biology of aging have identified several genetic and pharmacological
interventions that appear to modulate the rate of aging in laboratory model organisms, but a …

[图书][B] Breed predispositions to disease in dogs and cats

A Gough, A Thomas, D O'Neill - 2018 - books.google.com
Breed Predispositions to Disease in Dogs and Cats, Third Edition provides a comprehensive
exploration of current knowledge of breed predispositions based on rigorous examination of …

Companion animals in comparative oncology: One Medicine in action

OA Garden, SW Volk, NJ Mason, JA Perry - The Veterinary Journal, 2018 - Elsevier
Comparative oncology is poised to have a far-reaching impact on both animals and human
beings with cancer. The field is gaining momentum and has repeatedly proven its utility in …