Thiazole-containing compounds as therapeutic targets for cancer therapy

PC Sharma, KK Bansal, A Sharma, D Sharma… - European journal of …, 2020 - Elsevier
In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

Targeting histone deacetylases with natural and synthetic agents: an emerging anticancer strategy

AK Singh, A Bishayee, AK Pandey - Nutrients, 2018 - mdpi.com
Cancer initiation and progression are the result of genetic and/or epigenetic alterations.
Acetylation-mediated histone/non-histone protein modification plays an important role in the …

Benzimidazole based derivatives as anticancer agents: Structure activity relationship analysis for various targets

G Satija, B Sharma, A Madan, A Iqubal… - Journal of …, 2022 - Wiley Online Library
Benzimidazole, the benzo derivative of imidazole, is a class of bicyclic aromatic organic
compound consisting of six‐membered benzene ring fused to five‐membered imidazole at 4 …

[HTML][HTML] Hepatocellular carcinoma: causes, mechanism of progression and biomarkers

AK Singh, R Kumar, AK Pandey - Current chemical genomics and …, 2018 - ncbi.nlm.nih.gov
Hepatocellular Carcinoma (HCC) is one of the most common malignant tumours in the
world. It is a heterogeneous group of a tumour that vary in risk factor and genetic and …

The application of histone deacetylases inhibitors in glioblastoma

R Chen, M Zhang, Y Zhou, W Guo, M Yi… - Journal of Experimental …, 2020 - Springer
The epigenetic abnormality is generally accepted as the key to cancer initiation. Epigenetics
that ensure the somatic inheritance of differentiated state is defined as a crucial factor …

Terminalia bellirica (Gaertn.) roxb.(Bahera) in health and disease: A systematic and comprehensive review

A Gupta, R Kumar, P Bhattacharyya, A Bishayee… - Phytomedicine, 2020 - Elsevier
Abstract Background Terminalia bellirica (Gaertn.) Roxb. is one of the oldest medicinal
herbs of India, Pakistan, Nepal, Bangladesh and Sri Lanka as well as South-East Asia. Its …

On topological indices and QSPR analysis of drugs used for the treatment of breast cancer

SAUH Bokhary, Adnan, MK Siddiqui… - Polycyclic Aromatic …, 2022 - Taylor & Francis
A topological index of graph G is a numerical quantity which describes its topology. If it is
applied to molecular structure of a chemical compounds then it reflects the theoretical …

Drug-metabolizing enzymes: role in drug resistance in cancer

G Kaur, SK Gupta, P Singh, V Ali, V Kumar… - Clinical and Translational …, 2020 - Springer
Although continuous researches are going on for the discovery of new chemotherapeutic
agents, resistance to these anticancer agents has made it really difficult to reach the fruitful …

Revealing quinquennial anticancer journey of morpholine: A SAR based review

F Arshad, MF Khan, W Akhtar, MM Alam… - European journal of …, 2019 - Elsevier
Morpholine, a six-membered heterocycle containing one nitrogen and one oxygen atom, is a
moiety of great significance. It forms an important intermediate in many industrial and …

Degree-based topological indices on anticancer drugs with QSPR analysis

MC Shanmukha, NS Basavarajappa, KC Shilpa… - Heliyon, 2020 - cell.com
From last two to three decades, the world is facing the threat of finding treatment for Cancer.
This disease is striking almost ten million people every year throughout the world …