Transposable elements (TEs) are selfish genetic units that typically encode proteins that
enable their proliferation in the genome and spread across individual hosts. Here we review …

Transposable elements (TEs) are abundant components of constitutive heterochromatin of
the most diverse evolutionarily distant organisms. TEs enrichment in constitutive …

Background Most eukaryotic genes are subject to alternative splicing (AS), which may
contribute to the production of protein variants or to the regulation of gene expression via …

Abstract ParameciumDB (https://paramecium. i2bc. paris-saclay. fr) is a community model
organism database for the genome and genetics of the ciliate Paramecium. ParameciumDB …

Summary Polycomb repressive complex 2 (PRC2) maintains transcriptionally silent genes in
a repressed state via deposition of histone H3K27-trimethyl (me3) marks. PRC2 has also …

The domestication of transposable elements has repeatedly occurred during evolution and
domesticated transposases have often been implicated in programmed genome …

DNA double-strand breaks (DSBs) are the most toxic DNA lesions given their oncogenic
potential. Nevertheless, programmed DSBs (prDSBs) contribute to several biological …

Ciliates are an interesting model system for investigating diverse functions of noncoding
RNAs, especially in genome defence pathways. During sexual development, the ciliate …

The term epigenetics is used for any layer of genetic information aside from the DNA base‐
sequence information. Mammalian epigenetic research increased our understanding of …

Gene duplication and diversification drive the emergence of novel functions during
evolution. Because of whole genome duplications, ciliates from the Paramecium aurelia …