Revealing lncRNA structures and interactions by sequencing-based approaches

X Qian, J Zhao, PY Yeung, QC Zhang… - Trends in biochemical …, 2019 - cell.com
Long noncoding RNAs (lncRNAs) have emerged as significant players in almost every level
of gene function and regulation. Thus, characterizing the structures and interactions of …

Long non-coding RNA: its evolutionary relics and biological implications in mammals: a review

JK Dhanoa, RS Sethi, R Verma, JS Arora… - Journal of animal …, 2018 - Springer
The central dogma of gene expression propounds that DNA is transcribed to mRNA and
finally gets translated into protein. Only 2–3% of the genomic DNA is transcribed to protein …

Non-coding RNAs: the new central dogma of cancer biology

PE Saw, X Xu, J Chen, EW Song - Science China Life Sciences, 2021 - Springer
The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

Non-coding RNAs in cardiovascular cell biology and atherosclerosis

F Fasolo, K Di Gregoli, L Maegdefessel… - Cardiovascular …, 2019 - academic.oup.com
Atherosclerosis underlies the predominant number of cardiovascular diseases and remains
a leading cause of morbidity and mortality worldwide. The development, progression and …

CRISPR/Cas9‐mediated mutagenesis of lncRNA1459 alters tomato fruit ripening

R Li, D Fu, B Zhu, Y Luo, H Zhu - The Plant Journal, 2018 - Wiley Online Library
With the development of high‐throughput sequencing, many long non‐coding RNA s (lnc
RNA s) have been found to play important roles in diverse biological processes. However …

Advanced liquid biopsy technologies for circulating biomarker detection

N Soda, BHA Rehm, P Sonar, NT Nguyen… - Journal of Materials …, 2019 - pubs.rsc.org
Liquid biopsy is a new diagnostic concept that provides important information for monitoring
and identifying tumor genomes in body fluid samples. Detection of tumor origin …

Comparative transcriptome analysis between resistant and susceptible tomato allows the identification of lnc RNA 16397 conferring resistance to Phytophthora …

J Cui, Y Luan, N Jiang, H Bao, J Meng - The plant journal, 2017 - Wiley Online Library
The rapid development of omics sequencing technology has facilitated the identification of
thousands of long non‐coding (lnc) RNA s in plant species, but the role of lnc RNA s in plant …

Long non-coding RNAs in Oral squamous cell carcinoma: biologic function, mechanisms and clinical implications

L Zhang, X Meng, X Zhu, D Yang, R Chen, Y Jiang… - Molecular cancer, 2019 - Springer
There is growing evidence that regions of the genome that cannot encode proteins play an
important role in diseases. These regions are usually transcribed into long non-coding …

RETRACTED ARTICLE: LINC01410-miR-532-NCF2-NF-kB feedback loop promotes gastric cancer angiogenesis and metastasis

JX Zhang, ZH Chen, DL Chen, XP Tian, CY Wang… - Oncogene, 2018 - nature.com
Dysregulation of non-coding RNAs, including miRNAs and lncRNAs has been reported to
play vital roles in gastric cancer (GC) carcinogenesis, but the mechanism involved is largely …

Biological relevance and therapeutic potential of G-quadruplex structures in the human noncoding transcriptome

M Tassinari, SN Richter, P Gandellini - Nucleic Acids Research, 2021 - academic.oup.com
Noncoding RNAs are functional transcripts that are not translated into proteins. They
represent the largest portion of the human transcriptome and have been shown to regulate …