Intracranial atherosclerotic stenosis (ICAS) is one of the most frequent causes of stroke
worldwide and confers one of the greatest risks of recurrent stroke compared with other …

Stroke is a devastating condition with significant morbidity and mortality worldwide.
Antithrombotic therapy plays a crucial role in both primary and secondary prevention of …

Background Comparisons between ticagrelor and clopidogrel for the secondary prevention
of stroke in CYP2C19 loss-of-function carriers have not been extensively performed …

Background Trials have evaluated the use of clopidogrel and aspirin to prevent stroke after
an ischemic stroke or transient ischemic attack (TIA). In a previous trial, ticagrelor was not …

Background and Purpose: Among patients with a transient ischemic attack or minor ischemic
strokes, those with ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the …

Antiplatelet medications remain a cornerstone of therapy for atherosclerotic cardiovascular
and cerebrovascular diseases. In primary prevention (patients with cardiovascular risk …

Importance The underenrollment of women in randomized clinical trials represents a threat
to the validity of the evidence supporting clinical guidelines and potential disparities in …

Importance Dual antiplatelet therapy (DAPT) with clopidogrel and aspirin is effective in
preventing recurrent strokes after minor ischemic stroke or transient ischemic attack (TIA) …

Increasing studies showed that several anti-platelet drugs turned out to be a promising
strategy for inflammatory response. In this study, we investigated the protective efficiency of …

Background and Purpose: This study tests whether patients with unruptured intracranial
aneurysm who underwent stent placement benefitted from platelet function monitoring …