Ivermectin–old drug, new tricks?

R Laing, V Gillan, E Devaney - Trends in parasitology, 2017 - cell.com
Ivermectin is one of the most important drugs in veterinary and human medicine for the
control of parasitic infection and was the joint focus of the 2015 Nobel Prize in Physiology or …

Neglected tropical diseases: progress towards addressing the chronic pandemic

DH Molyneux, L Savioli, D Engels - The Lancet, 2017 - thelancet.com
The concept of neglected tropical diseases (NTDs) emerged more than a decade ago and
has been recognised as a valid way to categorise diseases that affect the poorest …

The public health control of scabies: priorities for research and action

D Engelman, PT Cantey, M Marks, AW Solomon… - The Lancet, 2019 - thelancet.com
Scabies is a parasitic disease of the skin that disproportionately affects disadvantaged
populations. The disease causes considerable morbidity and leads to severe bacterial …

A trial of a triple-drug treatment for lymphatic filariasis

CL King, J Suamani, N Sanuku… - … England Journal of …, 2018 - Mass Medical Soc
Abstract Background The World Health Organization has targeted lymphatic filariasis for
global elimination by 2020 with a strategy of mass drug administration. This trial tested …

Exploring the binding efficacy of ivermectin against the key proteins of SARS-CoV-2 pathogenesis: an in silico approach

A Choudhury, NC Das, R Patra, M Bhattacharya… - Future …, 2021 - Taylor & Francis
Aim: COVID-19 is currently the biggest threat to mankind. Recently, ivermectin (a US FDA-
approved antiparasitic drug) has been explored as an anti-SARS-CoV-2 agent. Herein, we …

[HTML][HTML] Safety of oral ivermectin during pregnancy: a systematic review and meta-analysis

P Nicolas, MF Maia, Q Bassat, KC Kobylinski… - The Lancet Global …, 2020 - thelancet.com
Background About 3· 7 billion doses of ivermectin have been distributed in mass drug
administration (MDA) campaigns globally over the past 30 years. At 10–100 times higher …

Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety

C Chaccour, F Hammann, NR Rabinovich - Malaria Journal, 2017 - Springer
Ivermectin is an endectocide that has been used broadly in single dose community
campaigns for the control of onchocerciasis and lymphatic filariasis for more than 30 years …

[图书][B] Guideline: alternative mass drug administration regimens to eliminate lymphatic filariasis

World Health Organization - 2017 - apps.who.int
GUIDELINE Page 1 GUIDELINE Alternative mass drug administration regimens to eliminate
lymphatic filariasis Page 2 Page 3 GUIDELINE Alternative mass drug administration regimens to …

Alternative treatment strategies to accelerate the elimination of onchocerciasis

M Boussinesq, G Fobi, AC Kuesel - International health, 2018 - academic.oup.com
The use of alternative (or complementary) treatment strategies (ATSs) ie differing from
annual community-directed treatment with ivermectin (CDTI) is required in some African foci …

Effectiveness of a triple-drug regimen for global elimination of lymphatic filariasis: a modelling study

MA Irvine, WA Stolk, ME Smith… - The Lancet Infectious …, 2017 - thelancet.com
Background Lymphatic filariasis is targeted for elimination as a public health problem by
2020. The principal approach used by current programmes is annual mass drug …