Oxygen delivering biomaterials for tissue engineering

AL Farris, AN Rindone, WL Grayson - Journal of materials chemistry B, 2016 - pubs.rsc.org
Tissue engineering (TE) has provided promising strategies for regenerating tissue defects,
but few TE approaches have been translated for clinical applications. One major barrier in …

Phase‐shift, stimuli‐responsive perfluorocarbon nanodroplets for drug delivery to cancer

N Rapoport - Wiley Interdisciplinary Reviews: Nanomedicine …, 2012 - Wiley Online Library
This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

Ultrasound triggered tumor oxygenation with oxygen-shuttle nanoperfluorocarbon to overcome hypoxia-associated resistance in cancer therapies

X Song, L Feng, C Liang, K Yang, Z Liu - Nano letters, 2016 - ACS Publications
Tumor hypoxia is known to be one of critical reasons that limit the efficacy of cancer
therapies, particularly photodynamic therapy (PDT) and radiotherapy (RT) in which oxygen …

Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions

N Rapoport, KH Nam, R Gupta, Z Gao, P Mohan… - Journal of Controlled …, 2011 - Elsevier
Perfluorocarbon nanoemulsions can deliver lipophilic therapeutic agents to solid tumors and
simultaneously provide for monitoring nanocarrier biodistribution via ultrasonography and/or …

Sono-promoted drug penetration and extracellular matrix modulation potentiate sonodynamic therapy of pancreatic ductal adenocarcinoma

H Xiao, X Li, B Li, Y Zhong, J Qin, Y Wang, S Han… - Acta Biomaterialia, 2023 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) exhibits difficult penetration of most drugs,
leading to a very poor therapeutic outcome with a quite low five-year survival rate. The …

Biomimetic nanoemulsions for oxygen delivery in vivo

J Zhuang, M Ying, K Spiekermann, M Holay… - Advanced …, 2018 - Wiley Online Library
Blood transfusion is oftentimes required for patients suffering from acute trauma or
undergoing surgical procedures in order to help maintain the body's oxygen levels. The …

A new era in oxygen therapeutics? From perfluorocarbon systems to haemoglobin-based oxygen carriers

NB Charbe, F Castillo, MM Tambuwala, P Prasher… - Blood Reviews, 2022 - Elsevier
Blood transfusion is the key to life in case of traumatic emergencies, surgeries and in several
pathological conditions. An important goal of whole blood or red blood cell transfusion is the …

Vaporization of perfluorocarbon droplets using optical irradiation

E Strohm, M Rui, I Gorelikov, N Matsuura… - Biomedical Optics …, 2011 - opg.optica.org
Micron-sized liquid perfluorocarbon (PFC) droplets are currently being investigated as
activatable agents for medical imaging and cancer therapy. After injection into the …

[HTML][HTML] Spanish Consensus Statement on alternatives to allogeneic blood transfusion: the 2013 update of the “Seville Document”

SR Leal-Noval, M Muñoz, M Asuero… - Blood …, 2013 - ncbi.nlm.nih.gov
-The use of restrictive transfusion strategies in nonbleeding, euvolaemic anaemic patients.-
Perioperative administration of tranexamic acid to patients undergoing cardiac surgery.-The …

Drug-loaded perfluorocarbon nanodroplets for ultrasound-mediated drug delivery

N Rapoport - Therapeutic ultrasound, 2016 - Springer
The interaction of nanoparticles with directed energy is a novel application in targeted drug
delivery. This chapter focuses on perfluorocarbon nanoemulsions, whose action in drug …