Paradigms of sleep deprivation (SD) and memory testing in rodents (laboratory rats and
mice) are here reviewed. The vast majority of these studies have been aimed at …

There is urgent need for the development of mechanistically different and less side-effect
prone antipsychotic compounds. The endocannabinoid system has been suggested to …

Cannabidiol (CBD), a non-psychotomimetic compound of the Cannabis sativa, has been
reported to have central therapeutic actions, such as antipsychotic and anxiolytic effects. We …

Schizophrenia is considered a debilitating neurodevelopmental psychiatric disorder and its
pharmacotherapy remains problematic without recent major advances. The development of …

Posttraumatic stress disorder (PTSD) is a devastating medical illness, for which currently
available pharmacotherapies have poor efficacy. Accumulating evidence from clinical and …

Learning to associate certain contexts with threat and adapting to changing environmental
contingencies by learning that such contexts are no longer associated with threat are both …

Rationale Dopamine D1-like receptor signalling is involved in contextual fear conditioning,
but the brain regions involved and its role in other contextual fear memory processes remain …

Schizophrenia and autism spectrum disorders (ASD) are psychiatric neurodevelopmental
disorders that cause high levels of functional disabilities. Also, the currently available …

Schizophrenia (SCZ) is a complex psychiatric disorder with severe impact on patient's
livelihood. In the last years, the importance of neuropeptides in SCZ and other CNS …

Schizophrenia is a debilitating psychiatric disorder which places a significant emotional and
economic strain on the individual and society-at-large. Unfortunately, currently available …