Cancer stem cells (CSCs) comprise the subpopulation of tumor bulk and acquire resistant to
conventional therapies and are considered as the primary tumor initiator cells. Nowadays …

Cell–cell communication is an essential mechanism for the maintenance and development
of various organs, including the female reproductive system. Today, it is well-known that the …

Despite a continuing debate about the existence of cancer stem cells (CSCs), recent
discoveries have provided further support for their existence and their roles in drug …

The identification of new molecular targets and biomarkers associated with high risk of
recurrence and response to therapy represents one of the main clinical challenges in the …

Endometrial cancer (EC) is the most frequent gynecological cancer. In patients with relapsed
and advanced disease, prognosis is still dismal and development of resistance is common …

Over the last few years, immunotherapy, in particular, immune checkpoint inhibitor therapy,
has revolutionized the treatment of several types of cancer. At the same time, the uptake in …

The family of aldehyde dehydrogenases (ALDHs) contains 19 isozymes and is involved in
the oxidation of endogenous and exogenous aldehydes to carboxylic acids, which …

At present, after extensive studies in the field of cancer, cancer stem cells (CSCs) have been
proposed as a major factor in tumor initiation, progression, metastasis, and recurrence …

MicroRNAs (miRNAs) are small non-coding RNAs composed of 18-25 nucleotides that
regulate the expression of approximately 30% of human protein coding genes …

The human endometrium is a unique, highly dynamic tissue that undergoes cyclic changes
of cell proliferation, differentiation, and death. Endometrial cancer is the most common …