Gingerols and shogaols: Important nutraceutical principles from ginger

RB Semwal, DK Semwal, S Combrinck, AM Viljoen - Phytochemistry, 2015 - Elsevier
Gingerols are the major pungent compounds present in the rhizomes of ginger (Zingiber
officinale Roscoe) and are renowned for their contribution to human health and nutrition …

Ginger for Healthy Ageing: A Systematic Review on Current Evidence of Its Antioxidant, Anti‐Inflammatory, and Anticancer Properties

M Ozkur, N Benlier, I Takan, C Vasileiou… - Oxidative medicine …, 2022 - Wiley Online Library
The world's population is ageing at an accelerated pace. Ageing is a natural, physiological
but highly complex and multifactorial process that all species in the Tree of Life experience …

Protective and therapeutic potential of ginger (Zingiber officinale) extract and [6]‐gingerol in cancer: A comprehensive review

RMT de Lima, AC Dos Reis… - Phytotherapy …, 2018 - Wiley Online Library
Natural dietary agents have attracted considerable attention due to their role in promoting
health and reducing the risk of diseases including cancer. Ginger, one of the most ancient …

A recent update on the multifaceted health benefits associated with ginger and its bioactive components

RH Ma, ZJ Ni, YY Zhu, K Thakur, F Zhang, YY Zhang… - Food & Function, 2021 - pubs.rsc.org
Due to recent lifestyle shifts and health discernments among consumers, synthetic drugs are
facing the challenge of controlling disease development and progression. Various medicinal …

6‐Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine‐Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti‐Inflammatory …

MA Alsahli, SA Almatroodi, A Almatroudi… - Mediators of …, 2021 - Wiley Online Library
Diethylnitrosamine (DEN) is a well‐known hepatocarcinogen, and its oral administration
causes severe liver damage including cancer. DEN induces the pathogenesis of the liver …

[HTML][HTML] Plants of the genus Zingiber: A review of their ethnomedicine, phytochemistry and pharmacology

M Deng, X Yun, S Ren, Z Qing, F Luo - Molecules, 2022 - mdpi.com
Plant of the genus Zingiber (Zingiberaceae) have primarily distributed in subtropical and
tropical Asia, South America and Africa. The species of this genus have been widely used as …

Quercetin induces cytochrome‐c release and ROS accumulation to promote apoptosis and arrest the cell cycle in G2/M, in cervical carcinoma: signal cascade and …

K Bishayee, S Ghosh, A Mukherjee… - Cell …, 2013 - Wiley Online Library
Objectives Small aromatic compounds like flavonoids can intercalate with DNA molecules
bringing about conformational changes leading to reduced replication and transcription …

Phytochemicals as potent modulators of autophagy for cancer therapy

MA Moosavi, A Haghi, M Rahmati, H Taniguchi… - Cancer Letters, 2018 - Elsevier
The dysregulation of autophagy is involved in the pathogenesis of a broad range of
diseases, and accordingly universal research efforts have focused on exploring novel …

[HTML][HTML] [6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling

EK Radhakrishnan, SV Bava, SS Narayanan, LR Nath… - PloS one, 2014 - journals.plos.org
We report mechanism-based evidence for the anticancer and chemopreventive efficacy of
[6]-gingerol, the major active principle of the medicinal plant, Ginger (Zingiber officinale), in …

Anticancer natural medicines: An overview of cell signaling and other targets of anticancer phytochemicals

MF Akhtar, A Saleem, A Rasul, MMFA Baig… - European Journal of …, 2020 - Elsevier
Therapies of cancer are as diverse as multifaceted the cancer is. Anticancer drugs include,
but not limited to synthetic, semisynthetic and natural drugs and monoclonal antibodies. A …