Congenital transmission of apicomplexan parasites: a review

M Rojas-Pirela, L Medina, MV Rojas… - Frontiers in …, 2021 - frontiersin.org
Apicomplexans are a group of pathogenic protists that cause various diseases in humans
and animals that cause economic losses worldwide. These unicellular eukaryotes are …

Lessons Learned for Pathogenesis, Immunology, and Disease of Erythrocytic Parasites: Plasmodium and Babesia

V Djokic, SC Rocha, N Parveen - Frontiers in cellular and infection …, 2021 - frontiersin.org
Malaria caused by Plasmodium species and transmitted by Anopheles mosquitoes affects
large human populations, while Ixodes ticks transmit Babesia species and cause …

Interleukin (IL)-21 in inflammation and immunity during parasitic diseases

S Solaymani-Mohammadi, L Eckmann… - Frontiers in cellular and …, 2019 - frontiersin.org
Parasitic diseases cause significant morbidity and mortality in the developing and
underdeveloped countries. No efficacious vaccines are available against most parasitic …

Animal models of the immunology and pathogenesis of human babesiosis

A Kumar, A Kabra, I Igarashi, PJ Krause - Trends in Parasitology, 2023 - cell.com
Animal models of human babesiosis have provided a basic understanding of the
immunological mechanisms that clear, or occasionally exacerbate, Babesia infection and …

The Cross-Species Immunity During Acute Babesia Co-Infection in Mice

I Zafar, EM Galon, D Kondoh, A Efstratiou… - Frontiers in Cellular …, 2022 - frontiersin.org
Babesiosis causes high morbidity and mortality in immunocompromised individuals. An
earlier study suggested that lethal Babesia rodhaini infection in murine can be evaded by …

Elucidating parasite and host-cell factors enabling Babesia infection in sickle red cells under hypoxic/hyperoxic conditions

D Beri, M Singh, M Rodriguez… - Blood …, 2023 - ashpublications.org
Sickle red blood cells (RBCs) represent a naturally existing host-cell resistance mechanism
to hemoparasite infections. We investigate the basis of this resistance using Babesia …

Tafenoquine for Relapsing Babesiosis: A Case Series

PJ Krause, R Rogers, MK Shah… - Clinical Infectious …, 2024 - academic.oup.com
Background Relapsing babesiosis often occurs in highly immunocompromised patients and
has been attributed to the acquisition of resistance against drugs commonly used for …

Sickle Cell Anemia and Babesia Infection

D Beri, M Singh, M Rodriguez, K Yazdanbakhsh… - Pathogens, 2021 - mdpi.com
Babesia is an intraerythrocytic, obligate Apicomplexan parasite that has, in the last century,
been implicated in human infections via zoonosis and is now widespread, especially in parts …

Babesia microti Confers Macrophage-Based Cross-Protective Immunity Against Murine Malaria

A Efstratiou, EMS Galon, G Wang, K Umeda… - Frontiers in cellular …, 2020 - frontiersin.org
Malaria and babesiosis, the two primary intraerythrocytic protozoan diseases of humans,
have been reported in multiple cases of co-infection in endemic regions. As the geographic …

[HTML][HTML] Altered parasite life-cycle processes characterize Babesia divergens infection in human sickle cell anemia

JR Cursino-Santos, M Singh, E Senaldi… - …, 2019 - ncbi.nlm.nih.gov
Babesia divergens is an intra-erythrocytic parasite that causes malaria-like symptoms in
infected people. As the erythrocyte provides the parasite with the infra-structure to grow and …