Diabetes mellitus and melatonin: Where are we?

R Patel, N Parmar, SP Palit, N Rathwa… - Biochimie, 2022 - Elsevier
Diabetes mellitus (DM) and diabetes-related complications are amongst the leading causes
of mortality worldwide. The international diabetes federation (IDF) has estimated 592 million …

β-cell replenishment: Possible curative approaches for diabetes mellitus

N Rathwa, R Patel, SP Palit, N Parmar, S Rana… - Nutrition, Metabolism …, 2020 - Elsevier
Aims Diabetes mellitus (DM) is a disorder of heterogeneous etiology marked by persistent
hyperglycemia. Exogenous insulin is the only treatment for type 1 diabetes (T1D). Islet …

Anti-inflammatory and protective effects of combined treatment with sitagliptin and melatonin in cardiac ischemia reperfusion injury in obese rats: Involvement of TLR-4 …

H Sun, Z Zhou, H Xuan, Z Yan - European Journal of …, 2021 - journals.sagepub.com
Background: Obesity is associated with an augmented risk of myocardial
ischemia/reperfusion (I/R) injury. Reduction of I/R injury by effective cardioprotective …

Melatonin postconditioning combined with sitagliptin exerts full cardioprotection in diabetic hearts of aged rats through an AMPK-dependent mechanism

R Song, J Ren, J Sun, M Li - Archives of Biological Sciences, 2021 - serbiosoc.org.rs
The presence of multiple comorbidities in patients facing myocardial ischemia-reperfusion
(IR) injury is the main obstacle for cardioprotection. This study investigated the effect of …