Computational principles and challenges in single-cell data integration
The development of single-cell multimodal assays provides a powerful tool for investigating
multiple dimensions of cellular heterogeneity, enabling new insights into development …
multiple dimensions of cellular heterogeneity, enabling new insights into development …
[HTML][HTML] Integration strategies of multi-omics data for machine learning analysis
Increased availability of high-throughput technologies has generated an ever-growing
number of omics data that seek to portray many different but complementary biological …
number of omics data that seek to portray many different but complementary biological …
Multi-omics data integration, interpretation, and its application
I Subramanian, S Verma, S Kumar… - … and biology insights, 2020 - journals.sagepub.com
To study complex biological processes holistically, it is imperative to take an integrative
approach that combines multi-omics data to highlight the interrelationships of the involved …
approach that combines multi-omics data to highlight the interrelationships of the involved …
State of the field in multi-omics research: from computational needs to data mining and sharing
Multi-omics, variously called integrated omics, pan-omics, and trans-omics, aims to combine
two or more omics data sets to aid in data analysis, visualization and interpretation to …
two or more omics data sets to aid in data analysis, visualization and interpretation to …
Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials
Abstract Characterization and integration of the genome, epigenome, transcriptome,
proteome and metabolome of different datasets is difficult owing to a lack of ground truth …
proteome and metabolome of different datasets is difficult owing to a lack of ground truth …
Life history strategies of soil bacterial communities across global terrestrial biomes
The life history strategies of soil microbes determine their metabolic potential and their
response to environmental changes. Yet these strategies remain poorly understood. Here …
response to environmental changes. Yet these strategies remain poorly understood. Here …
Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets
Multi‐omics studies promise the improved characterization of biological processes across
molecular layers. However, methods for the unsupervised integration of the resulting …
molecular layers. However, methods for the unsupervised integration of the resulting …
Integrated omics: tools, advances and future approaches
With the rapid adoption of high-throughput omic approaches to analyze biological samples
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …
Multi-omic and multi-view clustering algorithms: review and cancer benchmark
N Rappoport, R Shamir - Nucleic acids research, 2018 - academic.oup.com
Recent high throughput experimental methods have been used to collect large biomedical
omics datasets. Clustering of single omic datasets has proven invaluable for biological and …
omics datasets. Clustering of single omic datasets has proven invaluable for biological and …
Multi-omics integration in biomedical research–A metabolomics-centric review
Recent advances in high-throughput technologies have enabled the profiling of multiple
layers of a biological system, including DNA sequence data (genomics), RNA expression …
layers of a biological system, including DNA sequence data (genomics), RNA expression …