The S100 family of proteins contains 25 known members that share a high degree of
sequence and structural similarity. However, only a limited number of family members have …

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

A major rate-limiting step in developing more effective immunotherapies for GBM is our
inadequate understanding of the cellular complexity and the molecular heterogeneity of …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Simple Summary In this review, we present a detailed discussion of how the plasminogen-
activation system is utilized by tumor cells in their unrelenting attack on the tissues …

The calcium-binding protein S100A4 promotes metastasis in several experimental animal
models, and S100A4 protein expression is associated with patient outcome in a number of …

The S100 proteins comprise at least 25 members, forming the largest group of EF-hand
signalling proteins in humans. Although the proteins are expressed in many tissues, each …

S100 protein family has been implicated in multiple stages of tumorigenesis and
progression. Among the S100 genes, 22 are clustered at chromosome locus 1q21, a region …

Our recent studies have shown that annexin II, expressed on the cell surface of osteoblasts,
plays an important role in the adhesion of hematopoietic stem cells (HSCs) to the endosteal …

Annexin A2 is a calcium-dependent, phospholipid-binding protein found on various cell
types. It is up-regulated in various tumor types and plays multiple roles in regulating cellular …