Longevity reflects the ability to maintain homeostatic conditions necessary for life as an
organism ages. A long-lived organism must contend not only with environmental hazards …

The observation that phenotypic variability is ubiquitous in isogenic populations has led to a
multitude of experimental and theoretical studies seeking to probe the causes and …

Cell growth and gene expression, two essential elements of all living systems, have long
been the focus of biophysical interrogation. Advances in experimental single-cell methods …

In isogenic microbial populations, phenotypic variability is generated by a combination of
stochastic mechanisms, such as gene expression, and deterministic factors, such as …

In exponentially proliferating populations of microbes, the population doubles at a rate less
than the average doubling time of a single-cell due to variability at the single-cell level. It is …

Asymmetric damage segregation (ADS) is ubiquitous among unicellular organisms: After a
mother cell divides, its two daughter cells receive sometimes slightly, sometimes strongly …

Cell growth and gene expression, two essential elements of all living systems, have long
been the focus of biophysical interrogation. Advances in experimental single-cell methods …

In the past decade, great strides have been made to quantify the dynamics of single-cell
growth and division in microbes. In order to make sense of the evolutionary history of these …

By diversifying, cells in a clonal population can together overcome the limits of individuals.
Diversity in single-cell growth rates allows the population to survive environmental stresses …

Microbial populations show striking diversity in cell growth morphology and lifecycle;
however, our understanding of how these factors influence the growth rate of cell …