Imaging biomarkers for clinical applications in neuro-oncology: current status and future perspectives
FY Chiu, Y Yen - Biomarker Research, 2023 - Springer
Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …
However, biomarkers are needed to be validated and approved, and even fewer are ever …
The complex interactions between the cellular and non-cellular components of the brain tumor microenvironmental landscape and their therapeutic implications
Glioblastoma (GBM), an aggressive high-grade glial tumor, is resistant to therapy and has a
poor prognosis due to its universal recurrence rate. GBM cells interact with the non-cellular …
poor prognosis due to its universal recurrence rate. GBM cells interact with the non-cellular …
Alternative normalization and analysis pipeline to address systematic bias in NanoString GeoMx Digital Spatial Profiling data
L van Hijfte, M Geurts, WR Vallentgoed, PHC Eilers… - Iscience, 2023 - cell.com
Spatial transcriptomics is a novel technique that provides RNA-expression data with tissue-
contextual annotations. Quality assessments of such techniques using end-user generated …
contextual annotations. Quality assessments of such techniques using end-user generated …
Mechanical properties in the glioma microenvironment: emerging insights and theranostic opportunities
AG Bhargav, JS Domino, R Chamoun… - Frontiers in …, 2022 - frontiersin.org
Gliomas represent the most common malignant primary brain tumors, and a high-grade
subset of these tumors including glioblastoma are particularly refractory to current standard …
subset of these tumors including glioblastoma are particularly refractory to current standard …
Histone deacetylase inhibitors impair glioblastoma cell motility and proliferation
Simple Summary Glioblastoma (GBM) is considered the deadliest brain tumor; with patients
displaying a high incidence of relapse and a 3-year survival of only 3–5%. For these …
displaying a high incidence of relapse and a 3-year survival of only 3–5%. For these …
A generalizable strategy for crosslinkable albumin-based hydrogels and application as potential anti-tumor nanoplatform
WW Lv, K Yang, J Yu, Y Wu, M Zhang… - Journal of …, 2023 - journals.sagepub.com
Albumin-based hydrogels have emerged as promising nanoparticle systems for the effective
delivery of hydrophobic anticancer drugs. Anti-cancer drugs often cause some adverse …
delivery of hydrophobic anticancer drugs. Anti-cancer drugs often cause some adverse …
Nanoparticle-Based Treatment in Glioblastoma
Glioblastoma (GB) is a malignant glioma associated with a mean overall survival of 12 to 18
months, even with optimal treatment, due to its high relapse rate and treatment resistance …
months, even with optimal treatment, due to its high relapse rate and treatment resistance …
Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities
A Karz, M Dimitrova, K Kleffman… - Pigment cell & …, 2022 - Wiley Online Library
Brain metastases are the most common brain malignancy. This review discusses the studies
presented at the third annual meeting of the Melanoma Research Foundation in the context …
presented at the third annual meeting of the Melanoma Research Foundation in the context …
Spatiotemporal insights into glioma oncostream dynamics: unraveling formation, stability, and disassembly pathways
Glioblastoma (GBM) remains a challenge in Neuro‐oncology, with a poor prognosis
showing only a 5% survival rate beyond two years. This is primarily due to its …
showing only a 5% survival rate beyond two years. This is primarily due to its …
Role of nerves in neurofibromatosis type 1-related nervous system tumors
LL Ge, MY Xing, HB Zhang, QF Li, ZC Wang - Cellular Oncology, 2022 - Springer
Abstract Background Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic
disorder that affects nearly 1 in 3000 infants. Neurofibromin inactivation and N F1 gene …
disorder that affects nearly 1 in 3000 infants. Neurofibromin inactivation and N F1 gene …