The placebo response in medicine: minimize, maximize or personalize?

P Enck, U Bingel, M Schedlowski, W Rief - Nature reviews Drug …, 2013 - nature.com
Our understanding of the mechanisms mediating or moderating the placebo response to
medicines has grown substantially over the past decade and offers the opportunity to …

Laboratory models of treatment relapse and mitigation techniques.

SN Wathen, CA Podlesnik - Behavior Analysis: Research and …, 2018 - psycnet.apa.org
Behavioral treatments arranging differential reinforcement effectively treat severe problem
behavior while interventions are underway. However, many events challenge these …

The neuropharmacology of relapse to food seeking: methodology, main findings, and comparison with relapse to drug seeking

SG Nair, T Adams-Deutsch, DH Epstein… - Progress in …, 2009 - Elsevier
Relapse to old, unhealthy eating habits is a major problem in human dietary treatments. The
mechanisms underlying this relapse are unknown. Surprisingly, until recently this clinical …

Blockade of 5-HT2A receptors in the medial prefrontal cortex attenuates reinstatement of cue-elicited cocaine-seeking behavior in rats

LA Pockros, NS Pentkowski, SE Swinford… - …, 2011 - Springer
Rationale The action of serotonin (5-HT) at the 5-HT 2A receptor subtype is thought to be
involved in cocaine-seeking behavior that is motivated by exposure to drug-associated cues …

Nuclear factor kappa B signaling within the rat nucleus accumbens core sex-dependently regulates cue-induced cocaine seeking and matrix metalloproteinase-9 …

MD Namba, MN Phillips, JL Neisewander… - Brain, behavior, and …, 2022 - Elsevier
Chronic drug self-administration and withdrawal are associated with distinct neuroimmune
adaptations that may increase drug craving and relapse vulnerability in humans. The …

Stimulation of medial prefrontal cortex serotonin 2C (5-HT2C) receptors attenuates cocaine-seeking behavior

NS Pentkowski, FD Duke, SM Weber… - …, 2010 - nature.com
Abstract Serotonin 2C receptor (5-HT 2C R) agonists administered systemically attenuate
both cocaine-primed and cue-elicited reinstatement of extinguished cocaine-seeking …

Placebo effects in the immune system

M Hadamitzky, W Sondermann, S Benson… - International review of …, 2018 - Elsevier
Even though knowledge and systematic application of placebo responses in the immune
system are sparse, this topic is of particular importance since it may aim at drug-dose …

[HTML][HTML] Taste-immune associative learning amplifies immunopharmacological effects and attenuates disease progression in a rat glioblastoma model

S Hetze, L Barthel, L Lückemann, HS Günther… - Brain, Behavior, and …, 2022 - Elsevier
Mechanistic target of rapamycin (mTOR)-signaling is one key driver of glioblastoma (GBM),
facilitating tumor growth by promoting the shift to an anti-inflammatory, pro-cancerogenic …

Upregulation of Arc mRNA expression in the prefrontal cortex following cue‐induced reinstatement of extinguished cocaine‐seeking behavior

AR Zavala, T Osredkar, JN Joyce, JL Neisewander - Synapse, 2008 - Wiley Online Library
Cocaine‐associated cues acquire incentive motivational effects that manifest as cue‐elicited
craving in humans and cocaine‐seeking behavior in rats. Here we examine the hypothesis …

Environmental living conditions introduced during forced abstinence alter cocaine-seeking behavior and Fos protein expression

KJ Thiel, NS Pentkowski, NA Peartree, MR Painter… - Neuroscience, 2010 - Elsevier
Environmental enrichment (EE) introduced during abstinence from cocaine self-
administration is protective in reducing cue-elicited incentive motivation for cocaine in rats …