The placebo response in medicine: minimize, maximize or personalize?
Our understanding of the mechanisms mediating or moderating the placebo response to
medicines has grown substantially over the past decade and offers the opportunity to …
medicines has grown substantially over the past decade and offers the opportunity to …
Laboratory models of treatment relapse and mitigation techniques.
SN Wathen, CA Podlesnik - Behavior Analysis: Research and …, 2018 - psycnet.apa.org
Behavioral treatments arranging differential reinforcement effectively treat severe problem
behavior while interventions are underway. However, many events challenge these …
behavior while interventions are underway. However, many events challenge these …
The neuropharmacology of relapse to food seeking: methodology, main findings, and comparison with relapse to drug seeking
SG Nair, T Adams-Deutsch, DH Epstein… - Progress in …, 2009 - Elsevier
Relapse to old, unhealthy eating habits is a major problem in human dietary treatments. The
mechanisms underlying this relapse are unknown. Surprisingly, until recently this clinical …
mechanisms underlying this relapse are unknown. Surprisingly, until recently this clinical …
Blockade of 5-HT2A receptors in the medial prefrontal cortex attenuates reinstatement of cue-elicited cocaine-seeking behavior in rats
LA Pockros, NS Pentkowski, SE Swinford… - …, 2011 - Springer
Rationale The action of serotonin (5-HT) at the 5-HT 2A receptor subtype is thought to be
involved in cocaine-seeking behavior that is motivated by exposure to drug-associated cues …
involved in cocaine-seeking behavior that is motivated by exposure to drug-associated cues …
Nuclear factor kappa B signaling within the rat nucleus accumbens core sex-dependently regulates cue-induced cocaine seeking and matrix metalloproteinase-9 …
MD Namba, MN Phillips, JL Neisewander… - Brain, behavior, and …, 2022 - Elsevier
Chronic drug self-administration and withdrawal are associated with distinct neuroimmune
adaptations that may increase drug craving and relapse vulnerability in humans. The …
adaptations that may increase drug craving and relapse vulnerability in humans. The …
Stimulation of medial prefrontal cortex serotonin 2C (5-HT2C) receptors attenuates cocaine-seeking behavior
NS Pentkowski, FD Duke, SM Weber… - …, 2010 - nature.com
Abstract Serotonin 2C receptor (5-HT 2C R) agonists administered systemically attenuate
both cocaine-primed and cue-elicited reinstatement of extinguished cocaine-seeking …
both cocaine-primed and cue-elicited reinstatement of extinguished cocaine-seeking …
Placebo effects in the immune system
M Hadamitzky, W Sondermann, S Benson… - International review of …, 2018 - Elsevier
Even though knowledge and systematic application of placebo responses in the immune
system are sparse, this topic is of particular importance since it may aim at drug-dose …
system are sparse, this topic is of particular importance since it may aim at drug-dose …
[HTML][HTML] Taste-immune associative learning amplifies immunopharmacological effects and attenuates disease progression in a rat glioblastoma model
S Hetze, L Barthel, L Lückemann, HS Günther… - Brain, Behavior, and …, 2022 - Elsevier
Mechanistic target of rapamycin (mTOR)-signaling is one key driver of glioblastoma (GBM),
facilitating tumor growth by promoting the shift to an anti-inflammatory, pro-cancerogenic …
facilitating tumor growth by promoting the shift to an anti-inflammatory, pro-cancerogenic …
Upregulation of Arc mRNA expression in the prefrontal cortex following cue‐induced reinstatement of extinguished cocaine‐seeking behavior
Cocaine‐associated cues acquire incentive motivational effects that manifest as cue‐elicited
craving in humans and cocaine‐seeking behavior in rats. Here we examine the hypothesis …
craving in humans and cocaine‐seeking behavior in rats. Here we examine the hypothesis …
Environmental living conditions introduced during forced abstinence alter cocaine-seeking behavior and Fos protein expression
KJ Thiel, NS Pentkowski, NA Peartree, MR Painter… - Neuroscience, 2010 - Elsevier
Environmental enrichment (EE) introduced during abstinence from cocaine self-
administration is protective in reducing cue-elicited incentive motivation for cocaine in rats …
administration is protective in reducing cue-elicited incentive motivation for cocaine in rats …