Organ transplantation is the most effective therapy for patients with end-stage disease.
Preservation solutions and techniques are crucial for donor organ quality, which is directly …

Hepatic ischemia reperfusion injury (IRI), a fascinating topic that has drawn a lot of interest in
the last few years, is a major complication caused by a variety of clinical situations, such as …

Ex situ normothermic machine perfusion (NMP) is increasingly used for viability assessment
of high‐risk donor livers, whereas dual hypothermic oxygenated machine perfusion …

Ex situ dual hypothermic oxygenated machine perfusion (DHOPE) and normothermic
machine perfusion (NMP) of donor livers may have a complementary effect when applied …

Hepatic ischemia-reperfusion injury is a major cause of liver transplant failure, and is of
increasing significance due to increased use of expanded criteria livers for transplantation …

Hypothermic oxygenated perfusion (HOPE) and normothermic perfusion are seen as distinct
techniques of ex situ machine perfusion of the liver. We aimed to demonstrate the feasibility …

Normothermic machine perfusion (NMP) enables viability assessment of donor livers prior to
transplantation. NMP is frequently performed by using human blood products including red …

In the face of a critical organ shortage in the Western world, various strategies are employed
to expand the donor pool for orthotopic liver transplantation (OLT). Among them is the …

Hemoglobin (Hb) plays its vital role through structural and functional properties
evolutionarily optimized to work within red blood cells, ie, the tetrameric assembly, well …

The medical device M101 is an extracellular hemoglobin featuring high oxygen-carrying
capabilities. Preclinical studies demonstrated its safety as an additive to organ preservation …