The retina, owing to its cellular anatomy and physical location, is susceptible to generating
reactive oxygen species (ROS), which are associated with several major retinal diseases …

Significance: Sulforaphane, produced by the hydrolytic conversion of glucoraphanin after
ingestion of cruciferous vegetables, particularly broccoli and broccoli sprouts, has been …

The significance of oxidative stress in the development of chronic neurodegenerative
diseases of the retina has become increasingly apparent in recent years. Reactive oxygen …

Vision loss causes a significant burden on individuals and communities on a financial,
emotional and social level. Common causes include age-related macular degeneration …

Myopia affected approximately 1.6 billion people worldwide in 2000, and it is expected to
increase to 2.5 billion by 2020. Although optical problems can be corrected by optics or …

Abstract “Omics” refers to high-throughput analyses of genes, proteins, or metabolites in a
biological system, and is increasingly used for ophthalmic research. These system-based …

Background Age-related macular degeneration (AMD) is the leading cause of blindness in
the elderly population and its pathogenesis has been associated with inflammatory damage …

The term retinitis pigmentosa (RP) describes a large group of hereditary retinopathies. From
a cellular view, retinal degeneration is prompted by an initial death of rods, followed later by …

Oxidative stress has been documented to be a key factor in the cause and progression of
different retinal diseases. Oxidative cellular unbalance triggers a sequence of reactions …

Age-associated macular degeneration (AMD) is a progressive eye disorder that leads to
irreversible impairment of central vision, and effective therapies are lacking. Here, we …