Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

Oral squamous cell carcinoma (OSCC) is a common malignancy of the head and neck
region. OSCC has a relatively low survival rate and the incidence of the disease is …

Five-year survival for human papilloma virus-unrelated head and neck squamous cell
carcinomas remain below 50%. We assessed the safety of administering combination …

Cancer associated fibroblasts (CAFs) and tumor associated macrophages (TAMs) are
among the most important and abundant players of the tumor microenvironment. CAFs as …

The immune landscape of a tumor is highly connected to patient prognosis and response to
treatment, but little is known about how natural killer (NK) cells predict overall survival (OS) …

The tumor microenvironment (TME) is comprised of many different cell populations, such as
cancer-associated fibroblasts and various infiltrating immune cells, and non-cell …

Receptor for activated C kinase 1 (RACK1) has been shown to promote oral squamous cell
carcinoma (OSCC) progression, and RACK1 expression levels have been negatively …

Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …

Simple Summary Tumor infiltrating lymphocytes (TILs) have been demonstrated as
prognostic biomarkers in multiple cancer types. Among the various TIL phenotypic sub …

Tertiary lymphoid structures (TLS) are ectopic lymphoid structures in cancers that are largely
associated with favourable prognosis. However, the prognostic value of TLSs in oral …