Anticancer potential of lichens' secondary metabolites

Z Solárová, A Liskova, M Samec, P Kubatka… - Biomolecules, 2020 - mdpi.com
Lichens produce different classes of phenolic compounds, including anthraquinones,
xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed …

Lichens as a repository of bioactive compounds: an open window for green therapy against diverse cancers

TUH Dar, SA Dar, SU Islam, ZA Mangral, R Dar… - Seminars in Cancer …, 2022 - Elsevier
Lichens, algae and fungi-based symbiotic associations, are sources of many important
secondary metabolites, such as antibiotics, anti-inflammatory, antioxidants, and anticancer …

Silymarin nanoformulation as potential anticancer agent in experimental Ehrlich ascites carcinoma-bearing animals

M El-Far, N Salah, A Essam, AO Abd El-Azim… - …, 2018 - Taylor & Francis
Aim: This study aimed to evaluate, for the first time the potential use of a safe biocompatible
nanoformulation of silymarin (SM) as antitumor agent and to provide its mechanism of action …

A review of anti-cancer and related properties of lichen-extracts and metabolites

AH Tripathi, N Negi, R Gahtori, A Kumari… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Background: Lichens are a composite consortium of a fungus and an alga. The symbiotic
organisms are naturally equipped with distinct characteristics as compared to constituting …

Changes in apoptosis-related gene expression profiles in cancer cell lines exposed to usnic acid lichen secondary metabolite

AB Dincsoy, DC Duman - Turkish Journal of Biology, 2017 - journals.tubitak.gov.tr
The presence of uninhibited side effects of cancer drugs often used in cancer treatment has
stimulated the search for alternative therapeutic approaches. Therefore, anticarcinogenic …

Antibacterial and anticancer activities of nine lichens of Indonesian Java Island

AS Nugraha, DK Pratoko, YD Damayanti… - Journal of Biologically …, 2019 - Taylor & Francis
Lichen is a unique composite organism that arises from algae and fungi symbiotic
relationship. There are 18,500 recorded lichen species worldwide but only limited number of …

Lichens exerts an anti-proliferative effect on human breast and lung cancer cells through induction of apoptosis

S Ozturk, M Erkisa, S Oran, E Ulukaya… - Drug and chemical …, 2021 - Taylor & Francis
Successful cancer treatment still requires new complexes or compounds from natural
sources. Therefore, we investigated anti-growth/apoptotic effects of methanol extracts of the …

Differential anti-proliferative and apoptotic effects of lichen species on human prostate carcinoma cells

B Goncu, E Sevgi, C Kizilarslan Hancer, G Gokay… - PLoS …, 2020 - journals.plos.org
Lichens are stable symbiotic associations between fungus and algae and/or cyanobacteria
that have different biological activities. Around 60% of anti-cancer drugs are derived from …

Potent and Selective Inhibitors of Human Monoamine Oxidase A from an Endogenous Lichen Fungus Diaporthe mahothocarpus

GS Jeong, PF Hillman, MG Kang, S Hwang, JE Park… - Journal of Fungi, 2021 - mdpi.com
Using 126 endogenous lichen fungus (ELF) extracts, inhibitory activities against monoamine
oxidases (MAOs) and cholinesterases (ChEs) were evaluated. Among them, extract ELF29 …

Lichen secondary metabolites: Synthesis pathways and biological activities

GÇ ÖZYİĞİTOĞLU, B AÇIKGÖZ… - Acta Biologica …, 2017 - actabiologicaturcica.com
Lichens, which are formed by symbiotic relationship between algae and fungi, synthesize
naturally many secondary metabolites with different properties and functions, in response to …