Infantile spasms (IS or epileptic spasms during infancy) were first described by Dr. William
James West (aka West syndrome) in his own son in 1841. While rare by definition (occurring …

Introduction Infantile spasm (IS) is an epileptic syndrome with typical onset within the first 2
years of life. This condition might be caused by several etiologies. IS is associated with …

Intestinal atresia is an under‐diagnosed congenital defect in cattle. It results in complete
occlusion of the intestinal lumen and, unless surgically corrected, results in death or …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that includes autism,
Asperger's syndrome, and pervasive developmental disorder. ASD is characterized by poor …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that includes autism,
Asperger's syndrome, and pervasive developmental disorder. Individuals with ASD may …

Background Genomic loci where recurrent pathogenic copy number variants are associated
with psychiatric phenotypes in the population may also be sensitive to the collective impact …

Infantile spasms (IS, epileptic spasms during infancy) represent a unique entity among
epilepsy syndromes. Both its clinical picture (brief spastic seizures) and electrographic …

Background Abnormal genome-wide methylation during embryogenesis is associated with
neural tube defects (NTDs) at birth. Long noncoding RNAs (lncRNAs) may be promising …

Infantile epileptic spasms syndrome (IESS) is a severe epileptic encephalopathy occurring
in infancy. It encompasses both West syndrome as well as infants presenting with epileptic …

Genetic generalized epilepsy (GGE) is a form of epilepsy that is potentially caused by
genetic factors. It accounts for 15-20% of all epilepsy worldwide and 18.7% of the epilepsy …