1, 3, 4-thiadiazole is a five-membered aromatic heterocycle containing two nitrogen atoms
and one sulfur atom. As a privileged scaffold, it has its unique chemical properties and …

DNA gyrase and topoisomerase IV (topo IV) inhibitors are among the most interesting
antibacterial drug classes without antibacterial pipeline representative. Twenty-four new …

Abstract Novel 5-amino-1, 2, 4-triazole derivatives and their cyclized 1, 2, 4-triazolo [1, 5-a]
pyrimidine analogues were designed, synthesized and evaluated for their antimicrobial …

Bacterial resistance associated to different antibiotics is a limitation for the treatment of
infections and this has stimulated the development of new antimicrobial agents. In this …

In this investigation, we synthesized the newly antipyrine-azole-S-alkyl and their reduction
derivatives that were screened for their antimicrobial activity and compared them with …

With the goal of obtaining a novel bioactive compound with significant antifungal activity, a
series of 1, 3, 4-thiadiazole derivatives (3a–3l) were synthesized and characterized. Due to …

Some substituted thioureas (6a–i) containing a 1, 3, 4-thiadiazole ring were synthesized by
the reaction of the corresponding substituted 2-amino-1, 3, 4-thiadiazoles 3a–i with p …

A rapid, efficient, and one-pot protocol has been developed for the synthesis of cyclized 2, 6-
dimethyl-5-substituted-thiazolo [3, 2-b]-s-triazoles (3a–c) through the interaction of 5-methyl …

Many organic chromophores possess excellent nonlinear optical (NLO) properties. In spite
of this, the performance of these chromophores in second-order nonlinear optical …

In the present study a series of novel 2-(substituted phenyl)-3-(5-phenyl-1, 3, 4-thiadiazol-2-
yl)-2, 3-dihydroquinazolin-4 (1H)-one derivatives were synthesized by refluxing isatoic …