Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …

Microneedles were first conceptualized for drug delivery many decades ago, but only
became the subject of significant research starting in the mid-1990's when microfabrication …

Many promising therapeutic agents are limited by their inability to reach the systemic
circulation, due to the excellent barrier properties of biological membranes, such as the …

Poly (vinyl alcohol) microneedles were fabricated, characterized, and applied to enhance in
vitro transdermal delivery of doxorubicin. The microneedles were fabricated using the …

Micro Electromechanical Systems (MEMS) based microfluidic devices have gained
popularity in biomedicine field over the last few years. In this paper, a comprehensive …

Microneedles are an efficient and minimally invasive approach to transdermal drug delivery
and extraction of skin interstitial fluid. Compared to solid microneedles made of silicon …

Microneedles were first conceptualized for drug delivery many decades ago, overcoming the
shortages and preserving the advantages of hypodermic needle and conventional …

Microelectromechanical system (MEMS)-based microneedles are an innovative way of drug
delivery that increases the permeability of the skin. It generates microscopic pores inside the …

The degree of saponification, which is a dissolution characteristic of poly (vinyl
alcohol)(PVA), is used to blend PVA to prepare a hydrogel microneedle (MN) patch. The MN …

Stratum corneum is the main obstacle for drugs to pass through the skin. Microneedles are
composed of arrays of micro-projections formed with different materials, generally ranging …