Why remission is not enough: underlying disease mechanisms in RA that prevent cure
Cure is the aspirational aim for the treatment of all diseases, including chronic inflammatory
conditions such as rheumatoid arthritis (RA); however, it has only been during the twenty …
conditions such as rheumatoid arthritis (RA); however, it has only been during the twenty …
[HTML][HTML] Implications the Role of miR-155 in the Pathogenesis of Autoimmune Diseases
S Pashangzadeh, M Motallebnezhad… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are small noncoding conserved RNAs containing 19 to 24 nucleotides
that are regulators of post-translational modifications and are involved in the majority of …
that are regulators of post-translational modifications and are involved in the majority of …
The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis
S Bala, T Csak, B Saha, J Zatsiorsky, K Kodys… - Journal of …, 2016 - Elsevier
Background & Aims Alcoholic liver disease (ALD) ranges from fatty liver to inflammation and
cirrhosis. miRNA-155 is an important regulator of inflammation. In this study, we describe the …
cirrhosis. miRNA-155 is an important regulator of inflammation. In this study, we describe the …
Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy
Y Li, Y Duo, J Bi, X Zeng, L Mei, S Bao… - International journal …, 2018 - Taylor & Francis
Introduction MicroRNA-155 (miR-155) is an oncogenic microRNA, which is upregulated in
many human cancers including colorectal cancer (CRC). Overexpression of miR-155 has …
many human cancers including colorectal cancer (CRC). Overexpression of miR-155 has …
[HTML][HTML] Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar …
YT Hsieh, YC Chou, PY Kuo, HW Tsai, YT Yen… - Journal of biomedical …, 2022 - Springer
Background Increasing evidences have suggested an important role of microRNAs
(miRNAs) in regulating cell death processes including NETosis and apoptosis. Dysregulated …
(miRNAs) in regulating cell death processes including NETosis and apoptosis. Dysregulated …
[HTML][HTML] miR-155 in the progression of lung fibrosis in systemic sclerosis
RB Christmann, A Wooten, P Sampaio-Barros… - Arthritis research & …, 2016 - Springer
Background MicroRNA (miRNA) control key elements of mRNA stability and likely contribute
to the dysregulated lung gene expression observed in systemic sclerosis associated …
to the dysregulated lung gene expression observed in systemic sclerosis associated …
The involvement of microRNAs in modulation of innate and adaptive immunity in systemic lupus erythematosus and lupus nephritis
M Honarpisheh, P Köhler… - Journal of …, 2018 - Wiley Online Library
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs), represent a family of RNA
molecules that do not translate into protein. Nevertheless, they have the ability to regulate …
molecules that do not translate into protein. Nevertheless, they have the ability to regulate …
[HTML][HTML] Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis
H Kitai, N Kato, K Ogami, S Komatsu, Y Watanabe… - BMC biology, 2022 - Springer
Background Combinatorial gene regulation by multiple microRNAs (miRNAs) is widespread
and closely spaced target sites often act cooperatively to achieve stronger repression …
and closely spaced target sites often act cooperatively to achieve stronger repression …
[HTML][HTML] miRNA-mediated control of B cell responses in immunity and SLE
SL Schell, ZSM Rahman - Frontiers in immunology, 2021 - frontiersin.org
Loss of B cell tolerance is central to autoimmune diseases such as systemic lupus
erythematosus (SLE). As such, the mechanisms involved in B cell development, maturation …
erythematosus (SLE). As such, the mechanisms involved in B cell development, maturation …
[HTML][HTML] Dietary vinegar prevents kidney stone recurrence via epigenetic regulations
W Zhu, Y Liu, Y Lan, X Li, L Luo, X Duan, M Lei… - …, 2019 - thelancet.com
Background Epidemiological evidence of over 9000 people suggests that daily intake of
vinegar whose principal bioactive component is acetic acid is associated with a reduced risk …
vinegar whose principal bioactive component is acetic acid is associated with a reduced risk …