[HTML][HTML] The “mosaic” embryo: misconceptions and misinterpretations in preimplantation genetic testing for aneuploidy

NR Treff, D Marin - Fertility and sterility, 2021 - Elsevier
Preimplantation genetic testing for aneuploidy (PGT-A) remains one of the most
controversial topics in reproductive medicine. With more than 40% of in vitro fertilization …

Non-invasive preimplantation genetic testing for aneuploidies: an update

L Navarro-Sánchez, C García-Pascual, C Rubio… - Reproductive …, 2022 - Elsevier
Aneuploidy is common among preimplantation human embryos used in assisted
reproductive technology. Because abnormal chromosome number can negatively affect …

[HTML][HTML] An update on non-invasive approaches for genetic testing of the preimplantation embryo

G Kakourou, T Mamas, C Vrettou… - Current …, 2022 - ncbi.nlm.nih.gov
Abstract Preimplantation Genetic Testing (PGT) aims to reduce the chance of an affected
pregnancy or improve success in an assisted reproduction cycle. Since the first established …

Concordance of PGT for aneuploidies between blastocyst biopsies and spent blastocyst culture medium

CL Xu, YQ Wei, QY Tan, Y Huang, JJ Wu, CY Li… - Reproductive …, 2023 - Elsevier
Research question Non-invasive preimplantation genetic testing for aneuploidies (niPGT-A)
avoids the possible detrimental impact of invasive PGT-A on embryo development and …

The embryo non-invasive pre-implantation diagnosis era: how far are we?

M Del Collado, GM Andrade, NJN Gonçalves… - Animal …, 2023 - SciELO Brasil
Advancements in assisted reproduction (AR) methodologies have allowed significant
improvements in live birth rates of women who otherwise would not be able to conceive …

Clinical application of noninvasive chromosomal screening for elective single-blastocyst transfer in frozen-thawed cycles

R Chen, N Tang, H Du, Y Yao, Y Zou, J Wang… - Journal of Translational …, 2022 - Springer
Background The objective of this study was to explore the clinical application of noninvasive
chromosomal screening (NICS) for elective single-blastocyst transfer (eSBT) in frozen …

Majority of transferred mosaic embryos developed healthy live births revealed by a preclinical study using embryonic morphology assessment and noninvasive PGT-A …

L Cai, Q Zeng, C Gao, W Wu, J Shen, BL Wu… - Journal of Assisted …, 2022 - Springer
Purpose This preclinical study aimed to evaluate whether using transferred mosaic embryos
(primarily selected by embryonic morphology assessment (EMA) and compared by the …

Association of blood pressure in the first-week of hospitalization and long-term mortality in patients with acute left ventricular myocardial infarction

Y Tang, S Liu, Y Shi, T He, X Sun, M Wu, Z Peng… - International journal of …, 2022 - Elsevier
Background Previous studies have shown that optimal blood pressure (BP) control is
necessary to outcomes in patients with acute myocardial infarction (AMI). Acute left …

Cell-free deoxyribonucleic acid analysis in preimplantation genetic testing

CM García-Pascual, L Navarro-Sánchez… - F&S Science, 2023 - Elsevier
Detection of chromosomal aneuploidies and monogenic disorders in preimplantation
embryos is essential for selecting the best embryo for transfer during in vitro fertilization to …

Embryonic cell-free DNA in spent culture medium: a non-invasive tool for aneuploidy screening of the corresponding embryos

A Sialakouma, I Karakasiliotis, V Ntala, N Nikolettos… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: Preimplantation genetic testing (PGT) for chromosomal screening, based
on embryo biopsy, has significant limitations. Cell-free DNA (cf-DNA) has been detected in …