Active DNA demethylation: many roads lead to Rome
SC Wu, Y Zhang - Nature reviews Molecular cell biology, 2010 - nature.com
DNA methylation is one of the best-characterized epigenetic modifications and has been
implicated in numerous biological processes, including transposable element silencing …
implicated in numerous biological processes, including transposable element silencing …
Epigenetic reprogramming in mammals
HD Morgan, F Santos, K Green… - Human molecular …, 2005 - academic.oup.com
Epigenetic marking systems confer stability of gene expression during mammalian
development. Genome-wide epigenetic reprogramming occurs at stages when …
development. Genome-wide epigenetic reprogramming occurs at stages when …
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
B Czermin, R Melfi, D McCabe, V Seitz, A Imhof… - Cell, 2002 - cell.com
Enhancer of Zeste is a Polycomb Group protein essential for the establishment and
maintenance of repression of homeotic and other genes. In the early embryo it is found in a …
maintenance of repression of homeotic and other genes. In the early embryo it is found in a …
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases
JR Whetstine, A Nottke, F Lan, M Huarte, S Smolikov… - Cell, 2006 - cell.com
Histone methylation regulates chromatin structure, transcription, and epigenetic state of the
cell. Histone methylation is dynamically regulated by histone methylases and demethylases …
cell. Histone methylation is dynamically regulated by histone methylases and demethylases …
Epigenetic reprogramming during early development in mammals
F Santos, W Dean - Reproduction, 2004 - rep.bioscientifica.com
Epigenetic modifications serve as an extension of the information content by which the
underlying genetic code may be interpreted. These modifications mark genomic regions and …
underlying genetic code may be interpreted. These modifications mark genomic regions and …
Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment
MD Stewart, J Li, J Wong - Molecular and cellular biology, 2005 - Am Soc Microbiol
Abstract Histone H3 lysine 9 (H3-K9) methylation has been shown to correlate with
transcriptional repression and serve as a specific binding site for heterochromatin protein 1 …
transcriptional repression and serve as a specific binding site for heterochromatin protein 1 …
[HTML][HTML] Dynamic chromatin modifications characterise the first cell cycle in mouse embryos
On fertilisation, gametes undergo epigenetic reorganisation and re-establish totipotency.
Here, we investigate links between chromatin remodelling and asymmetric maintenance of …
Here, we investigate links between chromatin remodelling and asymmetric maintenance of …
Plasmodium falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The
malaria parasite Plasmodium falciparum employs antigenic variation of the major surface …
malaria parasite Plasmodium falciparum employs antigenic variation of the major surface …
MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing
CV Andreu-Vieyra, R Chen, JE Agno, S Glaser… - PLoS …, 2010 - journals.plos.org
During gametogenesis and pre-implantation development, the mammalian epigenome is
reprogrammed to establish pluripotency in the epiblast. Here we show that the histone 3 …
reprogrammed to establish pluripotency in the epiblast. Here we show that the histone 3 …
Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana
JP Jackson, L Johnson, Z Jasencakova, X Zhang… - Chromosoma, 2004 - Springer
The Arabidopsis KRYPTONITE gene encodes a member of the Su (var) 3-9 family of histone
methyltransferases. Mutations of kryptonite cause a reduction of methylated histone H3 …
methyltransferases. Mutations of kryptonite cause a reduction of methylated histone H3 …