Catheter ablation for atrial fibrillation (AF) has emerged as an important rhythm-control
strategy and is by far the most common cardiac ablation procedure performed worldwide …

The understanding of atrial fibrillation (AF) evolved from a sole rhythm disturbance towards
the complex concept of a cardiomyopathy based on arrhythmia substrates. There is …

Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains
difficult and AF-related complications cause unacceptable morbidity and mortality even on …

Atrial fibrillation (AF)—the most common arrhythmia—significantly increases the risk of
stroke and heart failure. Although catheter ablation can restore normal heart rhythms …

For both the atria and ventricles, fibrosis is generally recognized as one of the key
determinants of conduction disturbances. By definition, fibrosis refers to an increased …

Introduction Success rates of catheter ablation in persistent atrial fibrillation (AF) remain
suboptimal. A better and more targeted ablation strategy is urgently needed to optimize …

The pathophysiologic mechanisms underlying atrial fibrillation (AF) are highly complex and
variable among sufferers of this arrhythmia. 1, 2 This can be attributable to the different risk …

A family history of atrial fibrillation constitutes a substantial risk of developing the disease,
however, the pathogenesis of this complex disease is poorly understood. We perform whole …

AF is a heterogeneous rhythm disorder that is related to a wide spectrum of etiologies and
has broad clinical presentations. Mechanisms underlying AF are complex and remain …

The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …