Necrotizing enterocolitis: Pathophysiology from a historical context

D Hackam, M Caplan - Seminars in pediatric surgery, 2018 - Elsevier
Necrotizing enterocolitis (NEC) continues to afflict approximately 7% of preterm infants born
weighing less than 1500 g, though recent investigations have provided novel insights into …

Evidence for maternal diet-mediated effects on the offspring microbiome and immunity: implications for public health initiatives

J Mirpuri - Pediatric research, 2021 - nature.com
Diets rich in saturated fats have become a staple globally. Fifty percent of women of
childbearing age in the United States are obese or overweight, with diet being a significant …

Translational advances in pediatric nutrition and gastroenterology: new insights from pig models

D Burrin, PT Sangild, B Stoll, T Thymann… - Annual review of …, 2020 - annualreviews.org
Pigs are increasingly important animals for modeling human pediatric nutrition and
gastroenterology and complementing mechanistic studies in rodents. The comparative …

Impact of toll-like receptor 4 signaling in necrotizing enterocolitis: the state of the science

B Mihi, M Good - Clinics in perinatology, 2019 - perinatology.theclinics.com
Since the emergence of early eukaryotic organisms, a plethora of sophisticated defense
mechanisms has evolved to protect the host from invading pathogens and to ensure species …

[HTML][HTML] Cell-Free Amniotic Fluid and Regenerative Medicine: Current Applications and Future Opportunities

CM Bowen, FS Ditmars, A Gupta, JA Reems, WS Fagg - Biomedicines, 2022 - mdpi.com
Amniotic fluid (AF) provides critical biological and physical support for the developing fetus.
While AF is an excellent source of progenitor cells with regenerative properties, recent …

IL‐17 in neonatal health and disease

SM Lawrence, JL Ruoss… - American Journal of …, 2018 - Wiley Online Library
Over the last few years, scientific interest in the cytokine IL‐17A has intensified as its role in
human health and disease has been elucidated. Discovered almost a quarter century ago …

Recent advances in necrotizing enterocolitis research: strategies for implementation in clinical practice

M Pammi, IG De Plaen… - Clinics in …, 2020 - perinatology.theclinics.com
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Robust increases in erythropoietin production by the hypoxic fetus is a response to protect the brain and other vital organs

KA Teramo, MM Klemetti, JA Widness - Pediatric research, 2018 - nature.com
Fetal erythropoietin (EPO), in addition to regulating erythropoiesis, has also tissue-protective
properties based on its anti-inflammatory, anti-apoptotic, antioxidant, and neurotrophic …

The administration of amnion-derived multipotent cell secretome ST266 protects against necrotizing enterocolitis in mice and piglets

CP Sodhi, R Ahmad, H Jia, WB Fulton… - American Journal …, 2022 - journals.physiology.org
Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal disease in
premature infants and is steadily rising in frequency. Patients who develop NEC have a very …

[HTML][HTML] Amniotic fluid and vaginal microbiota in pregnant women with gestational diabetes mellitus by metagenomics

W Zheng, Y Huang, D Li, D Hu, C Jin, A Sadykova… - Medicine in …, 2023 - Elsevier
Aims To compared the amniotic fluid and vaginal microbiota of pregnant women, who
developed gestational diabetes mellitus to those who did not, and explored if any …