[HTML][HTML] Pernicious anemia: the hematological presentation of a multifaceted disorder caused by cobalamin deficiency
G Esposito, L Dottori, G Pivetta, I Ligato, E Dilaghi… - Nutrients, 2022 - mdpi.com
Pernicious anemia is still a neglected disorder in many medical contexts and is
underdiagnosed in many patients. Pernicious anemia is linked to but different from …
underdiagnosed in many patients. Pernicious anemia is linked to but different from …
Apoptosis in gastric epithelium induced byHelicobacter pyloriinfection: implications in gastric carcinogenesis
OBJECTIVES: Helicobacter pylori is an identified carcinogen for gastric cancer, however, the
underlying mechanisms remain to be defined. In this review, we sought to elucidate the role …
underlying mechanisms remain to be defined. In this review, we sought to elucidate the role …
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
KW McCracken, EM Catá, CM Crawford, KL Sinagoga… - Nature, 2014 - nature.com
Gastric diseases, including peptic ulcer disease and gastric cancer, affect 10% of the world's
population and are largely due to chronic Helicobacter pylori infection,,. Species differences …
population and are largely due to chronic Helicobacter pylori infection,,. Species differences …
[PDF][PDF] Genomic and epigenomic profiling of high-risk intestinal metaplasia reveals molecular determinants of progression to gastric cancer
Intestinal metaplasia (IM) is a pre-malignant condition of the gastric mucosa associated with
increased gastric cancer (GC) risk. We performed (epi) genomic profiling of 138 IMs from …
increased gastric cancer (GC) risk. We performed (epi) genomic profiling of 138 IMs from …
Autoimmune gastritis: long-term natural history in naïve Helicobacter pylori-negative patients
M Rugge, L Bricca, S Guzzinati, D Sacchi, M Pizzi… - Gut, 2023 - gut.bmj.com
Objective Autoimmune gastritis (AIG) is an immunomediated disease targeting parietal cells,
eventually resulting in oxyntic-restricted atrophy. This long-term follow-up study aimed at …
eventually resulting in oxyntic-restricted atrophy. This long-term follow-up study aimed at …
Acid and the basis for cellular plasticity and reprogramming in gastric repair and cancer
JB Sáenz, JC Mills - Nature Reviews Gastroenterology & Hepatology, 2018 - nature.com
Subjected to countless daily injuries, the stomach still functions as a remarkably efficient
digestive organ and microbial filter. In this Review, we follow the lead of the earliest …
digestive organ and microbial filter. In this Review, we follow the lead of the earliest …
Prevalence of gastric precancerous conditions: a systematic review and meta-analysis
L Marques-Silva, M Areia, L Elvas… - European journal of …, 2014 - journals.lww.com
Several reports of estimates for precancerous conditions for gastric adenocarcinoma can be
found in the current literature. Our aim was to systematically review and estimate the …
found in the current literature. Our aim was to systematically review and estimate the …
AGA technical review on gastric intestinal metaplasia—epidemiology and risk factors
Gastric cancer remains the third leading cause of cancer-related mortality and the fifth most
common cancer worldwide. 1 There is marked global variation of disease with areas of high …
common cancer worldwide. 1 There is marked global variation of disease with areas of high …
Current understanding of SPEM and its standing in the preneoplastic process
VG Weis, JR Goldenring - Gastric cancer, 2009 - Springer
Gastric cancer is the second leading cause of cancer-related death worldwide, but the
details of gastric carcinogenesis remain unclear. In humans, two preneoplastic metaplasias …
details of gastric carcinogenesis remain unclear. In humans, two preneoplastic metaplasias …
[HTML][HTML] The transcription factor MIST1 is a novel human gastric chief cell marker whose expression is lost in metaplasia, dysplasia, and carcinoma
JKM Lennerz, SH Kim, EL Oates, WJ Huh… - The American journal of …, 2010 - Elsevier
The lack of reliable molecular markers for normal differentiated epithelial cells limits
understanding of human gastric carcinogenesis. Recognized precursor lesions for gastric …
understanding of human gastric carcinogenesis. Recognized precursor lesions for gastric …