[HTML][HTML] Plant exosome-like nanovesicles: emerging therapeutics and drug delivery nanoplatforms

HA Dad, TW Gu, AQ Zhu, LQ Huang, LH Peng - Molecular Therapy, 2021 - cell.com
Plant exosome-like nanovesicles, being innately replete with bioactive lipids, proteins, RNA,
and other pharmacologically active molecules, offer unique morphological and …

The long road toward COVID-19 herd immunity: vaccine platform technologies and mass immunization strategies

LSF Frederiksen, Y Zhang, C Foged… - Frontiers in …, 2020 - frontiersin.org
There is an urgent need for effective countermeasures against the current emergence and
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …

Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

BJ Ward, P Gobeil, A Séguin, J Atkins, I Boulay… - Nature medicine, 2021 - nature.com
Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are being
deployed, but the global need greatly exceeds the supply, and different formulations might …

Non-viral COVID-19 vaccine delivery systems

KS Park, X Sun, ME Aikins, JJ Moon - Advanced drug delivery reviews, 2021 - Elsevier
The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …

Plant-derived natural products for drug discovery: current approaches and prospects

N Nasim, IS Sandeep, S Mohanty - The Nucleus, 2022 - Springer
Nature has abundant source of drugs that need to be identified/purified for use as essential
biologics, either individually or in combination in the modern medical field. These drugs are …

Efficacy, immunogenicity, and safety of a plant-derived, quadrivalent, virus-like particle influenza vaccine in adults (18–64 years) and older adults (≥ 65 years): two …

BJ Ward, A Makarkov, A Séguin, S Pillet, S Trépanier… - The Lancet, 2020 - thelancet.com
Background Seasonal influenza remains a substantial public health threat despite the
availability of egg-derived and other vaccines. Plant-based manufacturing might address …

Molecular farming–the slope of enlightenment

R Fischer, JF Buyel - Biotechnology advances, 2020 - Elsevier
Molecular farming can be defined as the use of plants to produce recombinant protein
products. The technology is now> 30 years old. The early promise of molecular farming was …

An overview of influenza viruses and vaccines

RF Nuwarda, AA Alharbi, V Kayser - Vaccines, 2021 - mdpi.com
Influenza remains one of the major public health concerns because it causes annual
epidemics and can potentially instigate a global pandemic. Numerous countermeasures …

Nanocarrier vaccines for SARS-CoV-2

J Machhi, F Shahjin, S Das, M Patel… - Advanced Drug Delivery …, 2021 - Elsevier
The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death
associated with substantive social, economic and societal impacts. Treatments rely on re …

Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection

CJ Batty, MT Heise, EM Bachelder… - Advanced drug delivery …, 2021 - Elsevier
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has led to an unprecedented effort toward the development of an effective …