[PDF][PDF] Biliary atresia: clinical and research challenges for the twenty‐first century

JA Bezerra, RG Wells, CL Mack, SJ Karpen… - …, 2018 - Wiley Online Library
Biliary atresia (BA) is a fibroinflammatory disease of the intrahepatic and extrahepatic biliary
tree. Surgical hepatic portoenterostomy (HPE) may restore bile drainage, but progression of …

Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal syndrome: 2021 practice guidance by the American Association …

SW Biggins, P Angeli, G Garcia‐Tsao, P Ginès… - …, 2021 - Wiley Online Library
This AASLD Guidance provides a data-supported approach to the management of ascites
and HRS. It differs from the AASLD Guidelines, which are supported by systematic reviews …

Nutritional needs and support for children with chronic liver disease

CH Yang, BJ Perumpail, ER Yoo, A Ahmed… - Nutrients, 2017 - mdpi.com
Malnutrition has become a dangerously common problem in children with chronic liver
disease, negatively impacting neurocognitive development and growth. Furthermore, many …

Diagnostic yield of newborn screening for biliary atresia using direct or conjugated bilirubin measurements

S Harpavat, JA Garcia-Prats, C Anaya, ML Brandt… - Jama, 2020 - jamanetwork.com
Importance Treating biliary atresia in newborns earlier can delay or prevent the need for
liver transplant; however, treatment typically occurs later because biliary atresia is difficult to …

Biliary atresia in 2021: epidemiology, screening and public policy

RA Schreiber, S Harpavat, JBF Hulscher… - Journal of Clinical …, 2022 - mdpi.com
Biliary atresia (BA) is a rare newborn liver disease with significant morbidity and mortality,
especially if not recognized and treated early in life. It is the most common cause of liver …

[PDF][PDF] Biliary atresia in children: update on disease mechanism, therapies, and patient outcomes

S Antala, SA Taylor - Clinics in liver disease, 2022 - Elsevier
Biliary atresia is a rare disease but remains the most common indication for pediatric liver
transplantation as there are no effective medical therapies to slow progression after …

[PDF][PDF] Transient elastography is useful in diagnosing biliary atresia and predicting prognosis after hepatoportoenterostomy

JF Wu, CS Lee, WH Lin, YM Jeng, HL Chen, YH Ni… - …, 2018 - Wiley Online Library
We investigated the utility of transient elastography (TE) for diagnosing biliary atresia (BA) in
cholestatic infants and predicting the outcome of BA. Forty‐eight cholestatic infants (9‐87 …

Malnutrition in pediatric chronic cholestatic disease: an up-to-date overview

M Tessitore, E Sorrentino, G Schiano Di Cola… - Nutrients, 2021 - mdpi.com
Despite recent advances, the causes of and effective therapies for pediatric chronic
cholestatic diseases remain elusive, and many patients progress to liver failure and need …

[PDF][PDF] Impacts of Early K asai Portoenterostomy on Short‐Term and Long‐Term Outcomes of Biliary Atresia

R Okubo, M Nio, H Sasaki… - Hepatology …, 2021 - Wiley Online Library
There are discrepancies regarding the clinical impact of age at Kasai portoenterostomy (KP)
on surgical outcomes. Hence, we re‐assessed the clinical significance of age at KP. We …

Update on investigations pertaining to the pathogenesis of biliary atresia

A Kilgore, CL Mack - Pediatric surgery international, 2017 - Springer
Biliary atresia is a devastating biliary disease of neonates that results in liver transplantation
for the vast majority. The etiology of biliary atresia is unknown and is likely multifactorial, with …