This article provides an overview of principles and barriers relevant to intracellular drug and
gene transport, accumulation and retention (collectively called as drug delivery) by means of …

Cell membrane components are organized as specialized domains involved in membrane-
associated events such as cell signaling, cell adhesion, and protein sorting. These …

Background Several eukaryotic proteins associated to the extracellular leaflet of the plasma
membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C …

A better molecular characterization of breast cell lines (BCL) may help discover new markers
to apply to tumour samples. We performed gene and protein expression profiling of 31 BCL …

Plasmodesmata (PD) are nano-sized membrane-lined channels controlling intercellular
communication in plants. Although progress has been made in identifying PD proteins, the …

A large body of evidence from the past decade supports the existence, in membrane from
animal and yeast cells, of functional microdomains that play important roles in protein …

Lipids tend to organize in mono or bilayer phases in a hydrophilic environment. While they
have long been thought to be incapable of coherent lateral segregation, it is now clear that …

In 1972, SJ Singer and GL Nicolson, 1 introducing the fluid mosaic model for the structure of
cell membranes, reported on experimental data suggesting that some proteins aggregated …

Humic substances have been widely used as plant growth promoters to improve the yield of
agricultural crops. However, the mechanisms underlying this effect remain unclear. Root …

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and a
leading cause of death in the US and worldwide. HCC remains a global health problem and …