Universal control mechanism regulating onset of M-phase

P Nurse - Nature, 1990 - nature.com
Universal control mechanism regulating onset of M-phase Page 1 REVIEW ARTICLE
Universal control mechanism regulating onset of M-phase Paul Nurse The onset of M-phase is …

Yeast carbon catabolite repression

JM Gancedo - Microbiology and molecular biology reviews, 1998 - Am Soc Microbiol
Glucose and related sugars repress the transcription of genes encoding enzymes required
for the utilization of alternative carbon sources; some of these genes are also repressed by …

Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis

O Gavet, J Pines - Developmental cell, 2010 - cell.com
Summary The CyclinB1-Cdk1 kinase is the catalytic activity at the heart of mitosis-promoting
factor (MPF), yet fundamental questions concerning its role in mitosis remained unresolved …

[PDF][PDF] Animal cell cycles and their control

C Norbury, P Nurse - Annual review of biochemistry, 1992 - academia.edu
CELL CYCLE CONTROL IN ANIMALS 443 established in many cases. Nonetheless, the
phosphorylation of nuclear lamins to promote nuclear disassembly (25, 31, 38-40), and the …

[HTML][HTML] A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae

V Guacci, D Koshland, A Strunnikov - Cell, 1997 - cell.com
The S. cerevisiae MCD1 (mitotic chromosome determinant) gene was identified in genetic
screens for genes important for chromosome structure. MCD1 is essential for viability and …

How proteolysis drives the cell cycle

RW King, RJ Deshaies, JM Peters, MW Kirschner - Science, 1996 - science.org
Oscillations in the activity of cyclin-dependent kinases (CDKs) promote progression through
the eukaryotic cell cycle. This review examines how proteolysis regulates CDK activity—by …

Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes

JY Hsu, ZW Sun, X Li, M Reuben, K Tatchell… - Cell, 2000 - cell.com
Phosphorylation of histone H3 at serine 10 occurs during mitosis and meiosis in a wide
range of eukaryotes and has been shown to be required for proper chromosome …

Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint

LA Shepperd, JC Meadows, AM Sochaj, TC Lancaster… - Current Biology, 2012 - cell.com
The spindle assembly checkpoint (SAC) is the major surveillance system that ensures that
sister chromatids do not separate until all chromosomes are correctly bioriented during …

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.

T Durfee, K Becherer, PL Chen, SH Yeh… - Genes & …, 1993 - genesdev.cshlp.org
The retinoblastoma protein (p110RB) interacts with many cellular proteins in complexes
potentially important for its growth-suppressing function. We have developed and used an …

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

RM Golsteyn, KE Mundt, AM Fry, EA Nigg - The Journal of cell biology, 1995 - rupress.org
Correct assembly and function of the mitotic spindle during cell division is essential for the
accurate partitioning of the duplicated genome to daughter cells. Protein phosphorylation …