Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
[HTML][HTML] Gasdermin D in pyroptosis
Pyroptosis is the process of inflammatory cell death. The primary function of pyroptosis is to
induce strong inflammatory responses that defend the host against microbe infection …
induce strong inflammatory responses that defend the host against microbe infection …
Programmed cell death tunes tumor immunity
The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …
the years revealed distinctive molecular mechanisms and functional consequences of …
[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19
JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …
NINJ1 mediates plasma membrane rupture during lytic cell death
N Kayagaki, OS Kornfeld, BL Lee, IB Stowe… - Nature, 2021 - nature.com
Plasma membrane rupture (PMR) is the final cataclysmic event in lytic cell death. PMR
releases intracellular molecules known as damage-associated molecular patterns (DAMPs) …
releases intracellular molecules known as damage-associated molecular patterns (DAMPs) …
The trinity of COVID-19: immunity, inflammation and intervention
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
Apoptosis (programmed cell death) and its signals-A review
E Obeng - Brazilian Journal of Biology, 2020 - SciELO Brasil
Apoptosis is a sequential order of cell death occurring regularly to ensure a homeostatic
balance between the rate of cell formation and cell death. However, a misplaced of this …
balance between the rate of cell formation and cell death. However, a misplaced of this …
The molecular virology of coronaviruses
E Hartenian, D Nandakumar, A Lari, M Ly… - Journal of Biological …, 2020 - ASBMB
Few human pathogens have been the focus of as much concentrated worldwide attention as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its …
The gasdermins, a protein family executing cell death and inflammation
The gasdermins are a family of recently identified pore-forming effector proteins that cause
membrane permeabilization and pyroptosis, a lytic pro-inflammatory type of cell death …
membrane permeabilization and pyroptosis, a lytic pro-inflammatory type of cell death …
Understanding SARS-CoV-2-mediated inflammatory responses: from mechanisms to potential therapeutic tools
Y Fu, Y Cheng, Y Wu - Virologica Sinica, 2020 - Springer
Currently there is no effective antiviral therapy for SARS-CoV-2 infection, which frequently
leads to fatal inflammatory responses and acute lung injury. Here, we discuss the various …
leads to fatal inflammatory responses and acute lung injury. Here, we discuss the various …