Post-traumatic osteoarthritis (PTOA) subsequent to joint injury accounts for over 12% of the
overall disease burden of OA, and higher in the most at-risk ankle and knee joints. Evidence …

Post‐traumatic osteoarthritis (PTOA) is defined by its development after joint injury. Factors
contributing to the risk of PTOA occurring, the rate of progression, and degree of associated …

Objectives The heterogeneity of meniscus cells and the mechanism of meniscus
degeneration is not well understood. Here, single-cell RNA sequencing (scRNA-seq) was …

Objective Meniscus injury increases the risk of osteoarthritis; however, the biologic
mechanism remains unknown. We hypothesized that pro-inflammatory stimulation of …

The aim of this study was to identify the molecules and pathways involved in the cross‐talk
between meniscus and synovium that may play a critical role in osteoarthritis (OA) …

Osteoarthritis (OA), the most common form of degenerative joint disease, is linked to high
morbidity. It is predicted to be the single greatest cause of disability in the general population …

Osteoarthritis (OA) is a multifaceted musculoskeletal disorder, with a high prevalence
worldwide. Articular cartilage and synovial membrane are among the main biological targets …

Meniscus injuries are extremely common with approximately one million patients
undergoing surgical treatment annually in the US alone. Upon injury, the outer zone of the …

Arthritis is a multifactorial disease for which current therapeutic intervention with high
efficacy remains challenging. Arthritis predominately affects articular joints, and cartilage …

The prognosis of non‐small cell lung cancer (NSCLC) is poor, since it has often
metastasized to distant organs by the time of diagnosis. Therefore, biomarkers predicting …