Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
[HTML][HTML] Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development
Executive summary Remarkable gains have been made in global health in the past 25
years, but progress has not been uniform. Mortality and morbidity from common conditions …
years, but progress has not been uniform. Mortality and morbidity from common conditions …
European Resuscitation Council Guidelines 2021: cardiac arrest in special circumstances
C Lott, A Truhlář, A Alfonzo, A Barelli… - Resuscitation, 2021 - Elsevier
Abstract These European Resuscitation Council (ERC) Cardiac Arrest in Special
Circumstances guidelines are based on the 2020 International Consensus on …
Circumstances guidelines are based on the 2020 International Consensus on …
[HTML][HTML] Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a …
T CRASH - The Lancet, 2019 - Elsevier
Background Tranexamic acid reduces surgical bleeding and decreases mortality in patients
with traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain …
with traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain …
Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial
K Baksaas-Aasen, LS Gall, J Stensballe… - Intensive care …, 2021 - Springer
Purpose Contemporary trauma resuscitation prioritizes control of bleeding and uses major
haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine …
haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine …
Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international …
Background Post-partum haemorrhage is the leading cause of maternal death worldwide.
Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients …
Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients …
Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury: a double-blind, placebo-controlled, randomized clinical trial
FX Guyette, JB Brown, MS Zenati, BJ Early-Young… - JAMA …, 2021 - jamanetwork.com
Importance In-hospital administration of tranexamic acid after injury improves outcomes in
patients at risk for hemorrhage. Data demonstrating the benefit and safety of the pragmatic …
patients at risk for hemorrhage. Data demonstrating the benefit and safety of the pragmatic …
The European guideline on management of major bleeding and coagulopathy following trauma
DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019 - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …
around the world, and post-traumatic bleeding remains a leading cause of potentially …
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial
Background Tranexamic acid can prevent death due to bleeding after trauma and post-
partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …
partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …
The European guideline on management of major bleeding and coagulopathy following trauma
R Rossaint, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2016 - Springer
Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …