Mammary gland 3D cell culture systems in farm animals

L Finot, E Chanat, F Dessauge - Veterinary Research, 2021 - Springer
In vivo study of tissue or organ biology in mammals is very complex and progress is slowed
by poor accessibility of samples and ethical concerns. Fortunately, however, advances in …

Cytotoxicity and DNA damage properties of tert-butylhydroquinone (TBHQ) food additive

M Eskandani, H Hamishehkar, JEN Dolatabadi - Food chemistry, 2014 - Elsevier
Tert-butylhydroquinone (TBHQ) was tested for potential cytotoxicity and genotoxicity upon
A549 lung cancer cells and Human Umbilical Vein Endothelial Cells (HUVEC). Cytotoxicity …

Protective Mechanism of Leucine and Isoleucine against H2O2‐Induced Oxidative Damage in Bovine Mammary Epithelial Cells

S Wu, X Liu, L Cheng, D Wang, G Qin… - Oxidative Medicine …, 2022 - Wiley Online Library
Leucine and isoleucine possess antioxidative and anti‐inflammatory properties. However,
their underlying protective mechanisms against oxidative damage remain unknown …

Deoxynivalenol induces apoptosis and disrupts cellular homeostasis through MAPK signaling pathways in bovine mammary epithelial cells

JY Lee, W Lim, S Park, J Kim, S You, G Song - Environmental pollution, 2019 - Elsevier
Abstract Deoxynivalenol (DON), a fungus-derived mycotoxin, also known as vomitoxin, is
found in a wide range of cereal grains and grain-based food products. The biological toxicity …

Effects of aflatoxin B1 on human breast cancer (MCF-7) cells: cytotoxicity, oxidative damage, metabolic, and immune-modulatory transcriptomic changes

A Aljazzar, WR El-Ghareeb, WS Darwish… - … Science and Pollution …, 2023 - Springer
Abstract Aflatoxin B1 (AFB1) is a potent mycotoxin that is commonly produced by molds such
as Aspergillus (A.) flavus and A. parasiticus. AFB1 is associated with several health adverse …

[PDF][PDF] Cellular interactions, metabolism, assessment and control of aflatoxins: an update

SM Hassan, SS Mughal, SK Hassan… - Comput Biol …, 2020 - researchgate.net
Aspergillus spp., the fungus containing aflatoxin, is commonly spread in nature and contains
severely polluted food sources from humans and wildlife, resulting in risks to health and …

Pterostilbene inhibits deoxynivalenol-induced oxidative stress and inflammatory response in bovine mammary epithelial cells

J Zhang, JM Wang, HT Fang, H Yu, Y Zhao, JL Shen… - Toxicon, 2021 - Elsevier
More and more studies have showed that tricothecene mycotoxin, deoxynivalenol (DON)
caused cytotoxicity in mammary alveolar cells-large T antigen cells (MAC-T). Therefore …

[HTML][HTML] Outbreak of aflatoxicosis in a dairy herd induced depletion in milk yield and high rates of abortion in Pakistan

F Penagos-Tabares, M Mahmood, M Sulyok, K Rafique… - Toxicon, 2024 - Elsevier
This case report investigated the outbreak of aflatoxicosis in a dairy herd in Pakistan, which
resulted in 30 abortions of 40 confirmed (75%) pregnant cows for 35 days and in 18.8 …

Exposure to aflatoxin B1 attenuates cell viability and induces endoplasmic reticulum-mediated cell death in a bovine mammary epithelial cell line (MAC-T)

W Park, MY Park, G Song, W Lim - Toxicology in Vitro, 2019 - Elsevier
Mammary gland epithelial cells play a key role in milk production in dairy cattle, which are
prone to feed contamination from microorganisms, especially pathogenic fungi and their …

Effect of aflatoxin B1 on BRCA1 and BRCA2 genes expression under in vitro cultured cell line of normal Human Mammary Epithelial Cells (HMEC)

S Moradi, H Azari, I Jafari Anarkooli… - Journal of Police …, 2015 - jpmed.ir
Background: Aflatoxins are carcinogenic compounds that are produced by Aspergillus flvaus
and A. parasiticus fungi growing on foods. Among variety of known aflatoxins, aflatoxin B1 …