Neurotransmitters are important biochemical molecules that control behavioral and
physiological functions in central and peripheral nervous system. Therefore, the analysis of …

Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Narcolepsy is a chronic sleep disorder that has a typical onset in adolescence and is
characterized by excessive daytime sleepiness, which can have severe consequences for …

Antihistamines targeting the histamine H1 receptor play an important role in improving and
maintaining the quality of life of patients with allergic rhinitis. For more effective and safer …

The hypothalamus is among the most phylogenetically conserved regions in the vertebrate
brain, reflecting its critical role in maintaining physiological and behavioural homeostasis. By …

Background Histaminergic neurons are crucial to maintain wakefulness, but their role in
cataplexy is unknown. We assessed the safety and efficacy of pitolisant, a histamine H3 …

This article addresses the clinical presentation, diagnosis, pathophysiology and
management of narcolepsy type 1 and 2, with a focus on recent findings. A low level of …

The hypothalamus, which regulates fundamental aspects of physiological homeostasis and
behavior, is a brain region that exhibits highly conserved anatomy across vertebrate …

This systematic review and meta-analysis examines the associations of allergic rhinitis with
sleep duration and sleep impairment. Observational studies published before August 2019 …

Despite varied etiologies and symptoms, several neurodegenerative diseases—specifically,
Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HDs)—share the common …