Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …

A growing number of epidemiological and experimental studies has established that
circadian disruption is strongly associated with psychiatric disorders, including major …

To assess the consistency of biological rhythms across studies, 57 public mouse liver tissue
timeseries totaling 1096 RNA-seq samples were obtained and analyzed. Only the control …

The integration of circadian and metabolic signals is essential for maintaining robust
circadian rhythms and ensuring efficient metabolism and energy use. Using Drosophila as …

Time of eating synchronizes circadian rhythms of metabolism and physiology. Inverted
feeding can uncouple peripheral circadian clocks from the central clock located in the …

Circadian and circannual cycles trigger physiological changes whose reflection on human
transcriptomes remains largely uncharted. We used the time and season of death of 932 …

Circadian rhythms are oscillations of behavior, physiology and metabolism in many
organisms. Recent advancements in omics technology make it possible for genome-wide …

Age-related macular degeneration (AMD) is the leading cause of central retinal vision loss
worldwide, with an estimated 1 in 10 people over the age of 55 showing early signs of the …

In mammals, circadian clocks are strictly suppressed during early embryonic stages, as well
as in pluripotent stem cells, by the lack of CLOCK/BMAL1-mediated circadian feedback …

Hepatocellular carcinoma (HCC) is among the most common and lethal form of cancer
worldwide. However, its diagnosis and treatment are still dissatisfactory, due to limitations in …