Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models

CA Orsini, DE Moorman, JW Young, B Setlow… - Neuroscience & …, 2015 - Elsevier
Over the past 20 years there has been a growing interest in the neural underpinnings of
cost/benefit decision-making. Recent studies with animal models have made considerable …

Developing treatments for cognitive deficits in schizophrenia: the challenge of translation

JW Young, MA Geyer - Journal of psychopharmacology, 2015 - journals.sagepub.com
Schizophrenia is a life-long debilitating mental disorder affecting tens of millions of people
worldwide. The serendipitous discovery of antipsychotics focused pharmaceutical research …

A review of risky decision-making in psychosis-spectrum disorders

JR Purcell, EN Herms, J Morales, WP Hetrick… - Clinical psychology …, 2022 - Elsevier
The investigation of risky decision-making has a prominent place in clinical science, with
sundry behavioral tasks aimed at empirically quantifying the psychological construct of risk …

Reduced dopamine transporter functioning induces high-reward risk-preference consistent with bipolar disorder

J Van Enkhuizen, BL Henry, A Minassian… - …, 2014 - nature.com
Individuals with bipolar disorder (BD) exhibit deleterious decision making, negatively
impacting their lives. Such aberrant decision making can be quantified using the Iowa …

Stress and decision making: neural correlates of the interaction between stress, executive functions, and decision making under risk

B Gathmann, FP Schulte, S Maderwald… - Experimental brain …, 2014 - Springer
Stress and additional load on the executive system, produced by a parallel working memory
task, impair decision making under risk. However, the combination of stress and a parallel …

Decision making under risk and under ambiguity in depressed suicide attempters, depressed non-attempters and healthy controls

EA Deisenhammer, SK Schmid, G Kemmler… - Journal of affective …, 2018 - Elsevier
Background A number of neuropsychological alterations have been found in patients who
have attempted suicide. Most studies investigating decision making (DM) abilities in suicide …

Dissecting negative symptoms in schizophrenia: opportunities for translation into new treatments

G Foussias, I Siddiqui, G Fervaha… - Journal of …, 2015 - journals.sagepub.com
Among the constellation of symptoms that characterize schizophrenia, negative symptoms
have emerged as a critical feature linked to the functional impairment experienced by …

A negative emotional and economic judgment bias in major depression

D Scheele, Y Mihov, O Schwederski, W Maier… - European archives of …, 2013 - Springer
Although major depression is projected to be among the top three causes of disability-
adjusted life years lost in 2030, relatively little is known concerning the extent to which …

A conceptual framework to develop a patient-reported experience measure of the quality of mental health care: A qualitative study of the PREMIUM project in France

S Fernandes, G Fond, X Zendjidjian, P Michel… - Journal of market …, 2021 - mdpi.com
Background: The objective of this study was to develop a conceptual framework to define a
domain map describing the experience of patients with severe mental illnesses (SMIs) on …

Among three different executive functions, general executive control ability is a key predictor of decision making under objective risk

J Schiebener, E Wegmann, B Gathmann… - Frontiers in …, 2014 - frontiersin.org
Executive functioning is supposed to have an important role in decision making under risk.
Several studies reported that more advantageous decision-making behavior was …