The mystical experience is a potential psychological mechanism to influence outcome in
psychedelic therapy. It includes features such as oceanic boundlessness, ego dissolution …

This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Psychedelics represent one of the most promising classes of experimental medicines for the
treatment of neuropsychiatric disorders due to their ability to promote neural plasticity and …

Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of
depression and related disorders. The ability to promote both structural and functional …

Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric
research and therapy. However, no modern studies have evaluated subjective and …

Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely
in controlled conditions, and can cause lasting psychological benefits with one or two …

This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

Responses to psychedelics are notoriously difficult to predict, yet significant work is currently
underway to assess their therapeutic potential and the level of interest in psychedelics …

Background: Recent years have seen a resurgence of research on the potential of
psychedelic substances to treat addictive and mood disorders. Historically and …