Drug delivery in leptomeningeal disease: Navigating barriers and beyond

N Arshad, N Biswas, J Gill, S Kesari, S Ashili - Drug delivery, 2024 - Taylor & Francis
Leptomeningeal disease (LMD) refers to the infiltration of cancer cells into the
leptomeningeal compartment. Leptomeninges are the two membranous layers, called the …

Posterior epidural migration of herniated lumbar disc fragment: a literature review

AE Elsharkawy, A Hagemann, PD Klassen - Neurosurgical review, 2019 - Springer
Herniated disc fragments' migration to posterior epidural locations is a very rare pathological
condition, and the mechanism is not well understood. Posterior epidural migration may lead …

Prx1  + and Hic1+ Mesenchymal Progenitors Are Present Within the Epidural Fat and Dura Mater and Participate in Dural Injury Repair

S Shah, S Mudigonda, TM Underhill… - Stem Cells …, 2022 - academic.oup.com
Epidural fat is commonly discarded during spine surgery to increase the operational field.
However, mesenchymal progenitor cells (MPCs) have now been identified in human …

Spontaneous epidural hematoma of cervical spine

F Salehpour, F Mirzaei, M Kazemzadeh… - International Journal of …, 2018 - ijssurgery.com
Spontaneous cervical epidural hematoma is an uncommon cause of acute spinal cord
compression. This is a rare idiopathic condition that leads to acute onset of neurologic …

[HTML][HTML] A 60-year-old man with gingivitis and poorly controlled diabetes developing low back pain 1 week following recovery from COVID-19 diagnosed with spinal …

ECP Chu, RJ Trager, ATC Chen… - The American Journal of …, 2022 - ncbi.nlm.nih.gov
Objective: Rare disease Background: Streptococcus oralis (S. oralis) is a gram-positive
bacterium and component of the oral microbiota that can rarely cause opportunistic infection …

Case 310: posterior epidural migration of a lumbar disk herniation

L Chiapparini, V Opancina, A Erbetta, B Pollo, M Broggi… - Radiology, 2023 - pubs.rsna.org
History A 49-year-old man presented with right foot drop, bilateral cruralgia mainly on the left
side, and genital and perianal hypoesthesia, which started suddenly 12 days before. After …

Proteoglycan 4 is present within the dura mater and produced by mesenchymal progenitor cells

S Mudigonda, S Shah, N Das, JM Corpuz… - Cell and Tissue …, 2022 - Springer
Mesenchymal progenitor cells (MPCs) have been recently identified in human and murine
epidural fat and have been hypothesized to contribute to the maintenance/repair …

[HTML][HTML] Systemic effects of fluoroscopically guided epidural steroid injection with dexamethasone

WY Kang, JW Lee, E Lee, Y Kang… - The Korean journal …, 2019 - synapse.koreamed.org
Background Epidural steroid injections (ESIs) have been widely used in managing spinal
pain. Dexamethasone has recently emerged as a useful drug in this setting, relative to …

Imaging of metastatic epidural spinal cord compression

J Bai, K Grant, A Hussien… - Frontiers in Radiology, 2022 - frontiersin.org
Metastatic epidural spinal cord compression develops in 5–10% of patients with cancer and
is becoming more common as advancement in cancer treatment prolongs survival in …

A Very Unusual Case of Physical Disability after Spinal Epidural Hematoma in the Course of Sport-Related Head Injury

J Gnus, S Fedorowicz, K Radzikowska, A Kołcz - Sustainability, 2022 - mdpi.com
Spinal epidural hematoma (SEH) is blood accumulation between the dura mater of the
spinal canal and the bone of the vertebrae. It is estimated to be an extremely rare incidence …