CNS tumors remain among the deadliest forms of cancer, resisting conventional and new
treatment approaches, with mortality rates staying practically unchanged over the past 30 …

Cancer immunotherapy is the great breakthrough in cancer treatment as it displayed
prolonged progression-free survival over conventional therapies, yet, to date, in only a …

Delivery of chemotherapy drugs specifically to cancer cells raises local drug doses in tumors
and therefore kills more cancer cells while reducing side effects in other tissues, thereby …

Droplet microfluidic techniques have long been known as a high-throughput approach for
cell manipulation. The capacity to compartmentalize cells into picolitre droplets in …

In the last decades three-dimensional (3D) in vitro cancer models have been proposed as a
bridge between bidimensional (2D) cell cultures and in vivo animal models, the gold …

The tumor microenvironment consists of diverse, complex etiological factors. The matrix
component of pancreatic ductal adenocarcinoma (PDAC) plays an important role not only in …

Cancer kills millions of individuals every year all over the world (Global Cancer
Observatory). The physiological and biomechanical processes underlying the tumor are still …

Cancer thrives in a complex environment where interactions between cellular and acellular
components, surrounding the tumor, play a crucial role in disease development and …

Despite significant improvements in the treatment of cancerous tumors in the last decades,
cancer remains one of the deadliest diseases worldwide. To overcome the shortcomings of …

At present, cancer is one of the leading causes of death worldwide. Treatment failure
remains one of the prime hurdles in cancer treatment due to the metastatic nature of cancer …