Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications

LCC Lee, KKW Lo - Journal of the American Chemical Society, 2022 - ACS Publications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …

Mitochondria-targeted smart AIEgens: Imaging and therapeutics

H Li, H Kim, C Zhang, S Zeng, Q Chen, L Jia… - Coordination Chemistry …, 2022 - Elsevier
Mitochondria are not only the main energy source of the cell but are also involved in the
regulation of important physiology and processes of diseases including cancers. Therefore …

Long-lived emissive probes for time-resolved photoluminescence bioimaging and biosensing

KY Zhang, Q Yu, H Wei, S Liu, Q Zhao… - Chemical …, 2018 - ACS Publications
In this Review article, we systematically summarize the design and applications of various
kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved …

The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications

FE Poynton, SA Bright, S Blasco, DC Williams… - Chemical Society …, 2017 - pubs.rsc.org
Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Detection of hypoxia in cancer models: significance, challenges, and advances

I Godet, S Doctorman, F Wu, DM Gilkes - Cells, 2022 - mdpi.com
The rapid proliferation of cancer cells combined with deficient vessels cause regions of
nutrient and O2 deprivation in solid tumors. Some cancer cells can adapt to these extreme …

Dinuclear metal complexes: multifunctional properties and applications

G Li, D Zhu, X Wang, Z Su, MR Bryce - Chemical Society Reviews, 2020 - pubs.rsc.org
The development of metal complexes for optoelectronic applications is a fertile area of
research. In contrast to the rigorous development of mononuclear metal complexes …

Recent advances on organelle specific Ru (II)/Ir (III)/Re (I) based complexes for photodynamic therapy

B Kar, U Das, N Roy, P Paira - Coordination Chemistry Reviews, 2023 - Elsevier
Organelle specificity is an important facet of more efficient and highly selective drugs with
reduced side effects which have now been the great challenge to the scientists. In …

Applications of ruthenium complex in tumor diagnosis and therapy

K Lin, ZZ Zhao, HB Bo, XJ Hao, JQ Wang - Frontiers in Pharmacology, 2018 - frontiersin.org
Ruthenium complexes are a new generation of metal antitumor drugs that are currently of
great interest in multidisciplinary research. In this review article, we introduce the …

Luminescent ruthenium (II) polypyridine complexes for a wide variety of biomolecular and cellular applications

J Shum, PKK Leung, KKW Lo - Inorganic Chemistry, 2019 - ACS Publications
Ruthenium (II) polypyridine complexes are one of the most extensively studied and
developed systems in the family of luminescent transition-metal complexes. Notably, there …