The plasminogen system has been implicated in clot lysis, wound healing, tissue
regeneration, cancer and many other processes that affect health and disease. The …

soluble urokinase Plasminogen Activator Receptor (suPAR) levels reflect inflammation and
elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in …

MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …

MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs that target
protein-coding mRNAs at the post-transcriptional level. Our previous studies suggest that mir …

Simple Summary In this review, we present a detailed discussion of how the plasminogen-
activation system is utilized by tumor cells in their unrelenting attack on the tissues …

Purpose Systemic levels of soluble urokinase-type plasminogen activator receptor (suPAR)
positively correlate with the activation level of the immune system. We reviewed the …

The antigen levels of components of the urokinase-type plasminogen activator (uPA) system
of plasminogen activation are correlated with prognosis in several types of cancers …

Recent advancements in cancer research have led to some major breakthroughs; however,
the impact on overall cancer-related death rate remains unacceptable, suggesting that …

The urokinase plasminogen activator (uPA) system consists of the serine protease uPA, its
glycolipid-anchored receptor, uPAR and its 2 serpin inhibitors, plasminogen activator …

The urokinase plasminogen activator (uPA) system (uPAS) consists of the uPA, its cognate
receptor (uPAR) and two specific inhibitors, the plasminogen activator inhibitor 1 (PAI-1) and …